Clinical and Radiographic Evaluation of Triple Antibiotic Paste Pulp Therapy Compared to Vitapex Pulpectomy in Non-vital Primary Molars

Overview

Journal Clin Exp Dent Res

Publisher Wiley

Specialty Dentistry

Date 2021 Jun 1

PMID 34060250

Citations 3

Authors

Ohoud T Sijini

Heba J Sabbagh

Khlood K Baghlaf

Amina M Bagher

Azzah A El-Housseiny

Najlaa M Alamoudi

Sara M Bagher

Affiliations

Soon will be listed here.

Abstract

Objectives: This study compared and evaluated the clinical and radiographic efficacy of non-instrumentation triple antibiotic paste pulp therapy and Vitapex pulpectomy in non-vital primary molars.

Material And Methods: Healthy, 5-9 years old children with at least one non-vital primary molar were included in the study. Molars were divided into two groups based on the subject's cooperation level. In the first group, molars received triple antibiotic paste, and a second group received Vitapex pulpectomy followed by a stainless-steel crown. Triple antibiotic paste was freshly prepared and proportioned in equal parts by volume (metronidazole, minocycline, and ciprofloxacin = 1:1:1) before the scheduled treatment. A clinical and radiographic examination was performed by two trained and calibrated pediatric dentists at the pre-operative baseline and the 6- and 12-month follow-up visits.

Results: A total of 28 molars received triple antibiotic paste pulp therapy and 20 received Vitapex pulpectomy. At the 6-month follow-up, the success rate among the molars in the triple antibiotic paste group was clinically (92.85%) and radiographically (85.71%) higher compared to the Vitapex group (91.67%, 62.50% respectively) with p = 0.89 and 0.55 respectively. At the 12-month follow-up, the molars in the triple antibiotic paste group showed lower clinical (95.45%) but higher radiographic success rate (72.73%) compared to the Vitapex group (100% and 62.50%) with (p = 0.85 and 0.47) respectively. None of the differences were statistically significant.

Conclusions: Both triple antibiotic paste and Vitapex can be clinically and radiographically effective in treating non-vital primary molars.

Citing Articles

The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses.

Alrayes N, Almaimouni Y, Tounsi A, Tarabzouni K, Alonaizan F, Ibrahim M Saudi Dent J. 2023; 35(6):575-588.

PMID: 37823084 PMC: 10562132. DOI: 10.1016/j.sdentj.2023.06.001.

Effect of Vitapex Combined with AH-Plus Paste on Inflammation in Middle-Aged and Elderly Patients with Periodontal-Endodontic Disease.

Hu R, Zhang F, Guo X, Jing Y, Lin X, Tian L Comput Math Methods Med. 2022; 2022:7540961.

PMID: 35813417 PMC: 9270133. DOI: 10.1155/2022/7540961.

Clinical and radiographic evaluation of triple antibiotic paste pulp therapy compared to Vitapex pulpectomy in non-vital primary molars.

Sijini O, Sabbagh H, Baghlaf K, Bagher A, El-Housseiny A, Alamoudi N Clin Exp Dent Res. 2021; 7(5):819-828.

PMID: 34060250 PMC: 8543458. DOI: 10.1002/cre2.434.

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