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The Role of the Allergist in the Management of Eosinophilic Esophagitis

Overview
Specialty Gastroenterology
Date 2021 Jun 1
PMID 34059605
Citations 4
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Abstract

Purpose Of Review: The purpose of this review is to provide the current understanding of the role of allergens/antigens, the use of allergy testing, and to elucidate the role of the allergist in the management of eosinophilic esophagitis (EoE).

Recent Findings: EoE is a T2 immune disorder that is part of the atopic march. EoE patients commonly have multiple concurrent allergic disorders. Recent studies demonstrate that, like other allergic diseases, epithelial barrier dysfunction plays a key role in EoE pathogenesis. Aero- and food allergens have been identified as EoE triggers. EoE management includes the assessment and avoidance of its instigating antigens. Due to the integrated T2 immune response in an allergic individual, proper EoE care should include the control of underlying atopic disorders. EoE is a complex disease that is optimally managed by a multidisciplinary approach.

Summary: This review provides an update on the role of the allergist in the clinical management of EoE.

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From Pathogenesis to Treatment: Targeting Type-2 Inflammation in Eosinophilic Esophagitis.

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Impact of environmental factors on the epidemiology of eosinophilic esophagitis in southwestern Europe (2007-2020).

Gratacos Gomez A, Ortega S, Canas A, Feo Brito F, Munoz Rodriguez J, Torrijos E J Allergy Clin Immunol Glob. 2023; 2(2):100088.

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Recent Trends in the Management of Eosinophilic Esophagitis: A Systematic Review.

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