Effect of Open Versus Closed Endotracheal Suctioning on Intracranial Pressure in Severe Brain-injured Children: Study Protocol for a Randomized Controlled Trial

Overview

Journal Nurs Open

Specialty Nursing

Date 2021 May 26

PMID 34037323

Citations 4

Authors

Yan Li

Xiaoyan Li

Zunjia Wen

Xin Zhang

Yingfei Liu

Li Wei

Affiliations

Soon will be listed here.

Abstract

Aim: To compare the effects and safety of open and closed endotracheal suction in children with severe brain injury.

Design: A single-blinding, single-centre randomized controlled trial (RCT).

Methods: The children with severe brain injury admitted to the intensive care unit (ICU) from 1 September 2020-31 August 2022 will be included. And a total of 172 children with severe brain injury are expected to be included. The intracranial pressure, SpO and heart rate before suctioning, at the end of suction, and at 5 and 10 min after suction, the estimated sputum volume for each suction, the incidence of ventilator-associated pneumonia, the duration of mechanical ventilation and the length of ICU stay will be analysed.

Results: This present RCT has been prospectively registered in China Clinical Trial Registry (http://www.chictr.org.cn, ChiCTR2000030963). This present study is expected to provide reliable evidence to the airway management in children with severe brain injury.

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Effect of open versus closed endotracheal suctioning on intracranial pressure in severe brain-injured children: Study protocol for a randomized controlled trial.

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