» Articles » PMID: 34036318

Increasing the Availability and Utilization of Reliable Data on Population Micronutrient (MN) Status Globally: the MN Data Generation Initiative

Overview
Journal Am J Clin Nutr
Publisher Elsevier
Date 2021 May 26
PMID 34036318
Citations 29
Authors
Affiliations
Soon will be listed here.
Abstract

Micronutrient (MN) deficiencies can produce a broad array of adverse health and functional outcomes. Young, preschool children and women of reproductive age in low- and middle-income countries are most affected by these deficiencies, but the true magnitude of the problems and their related disease burdens remain uncertain because of the dearth of reliable biomarker information on population MN status. The reasons for this lack of information include a limited understanding by policy makers of the importance of MNs for human health and the usefulness of information on MN status for program planning and management; insufficient professional capacity to advocate for this information and design and implement related MN status surveys; high costs and logistical constraints involved in specimen collection, transport, storage, and laboratory analyses; poor access to adequately equipped and staffed laboratories to complete the analyses reliably; and inadequate capacity to interpret and apply this information for public health program design and evaluation. This report describes the current situation with regard to data availability, the reasons for the lack of relevant information, and the steps needed to correct this situation, including implementation of a multi-component MN Data Generation Initiative to advocate for critical data collection and provide related technical assistance, laboratory services, professional training, and financial support.

Citing Articles

Micronutrient dose response (MiNDR) study among women of reproductive age and pregnant women in rural Bangladesh: study protocol for double-blind, randomised, controlled trials.

Siddiqua T, Schulze K, Hasan S, Ahsan K, Bandyopadhyay S, Zavala E BMJ Open. 2025; 15(1):e090108.

PMID: 39755576 PMC: 11749533. DOI: 10.1136/bmjopen-2024-090108.


Global estimation of dietary micronutrient inadequacies: a modelling analysis.

Passarelli S, Free C, Shepon A, Beal T, Batis C, Golden C Lancet Glob Health. 2024; 12(10):e1590-e1599.

PMID: 39218000 PMC: 11426101. DOI: 10.1016/S2214-109X(24)00276-6.


Development of a standardized consensus lexicon for terms related to micronutrient programs.

Hlaing L, Bourassa M, Brown K, Atkin R, Osendarp S, Gupta A PLoS One. 2024; 19(8):e0308230.

PMID: 39213298 PMC: 11364245. DOI: 10.1371/journal.pone.0308230.


Can micronutrient requirements be met by diets from sustainable sources: outcomes of dietary modelling studies using diet optimization.

Leonard U, Kiely M Ann Med. 2024; 56(1):2389295.

PMID: 39129219 PMC: 11321105. DOI: 10.1080/07853890.2024.2389295.


The Impact of Delayed Processing of Chilled Whole Blood Specimens on the Measurement of Nutritional Biomarkers in the United Kingdom National Diet and Nutrition Survey Rolling Programme.

Jones K, Meadows S, Parkington D, Collins D, Bates B, Koulman A J Nutr. 2024; 154(9):2818-2826.

PMID: 39004224 PMC: 11393162. DOI: 10.1016/j.tjnut.2024.07.008.


References
1.
Tinker S, Hamner H, Qi Y, Crider K . U.S. women of childbearing age who are at possible increased risk of a neural tube defect-affected pregnancy due to suboptimal red blood cell folate concentrations, National Health and Nutrition Examination Survey 2007 to 2012. Birth Defects Res A Clin Mol Teratol. 2015; 103(6):517-26. PMC: 4515959. DOI: 10.1002/bdra.23378. View

2.
Lynch S, Pfeiffer C, Georgieff M, Brittenham G, Fairweather-Tait S, Hurrell R . Biomarkers of Nutrition for Development (BOND)-Iron Review. J Nutr. 2018; 148(suppl_1):1001S-1067S. PMC: 6297556. DOI: 10.1093/jn/nxx036. View

3.
Bath S . The effect of iodine deficiency during pregnancy on child development. Proc Nutr Soc. 2019; 78(2):150-160. DOI: 10.1017/S0029665118002835. View

4.
Vosti S, Kagin J, Engle-Stone R, Luo H, Tarini A, Clermont A . Strategies to achieve adequate vitamin A intake for young children: options for Cameroon. Ann N Y Acad Sci. 2019; 1465(1):161-180. PMC: 7187426. DOI: 10.1111/nyas.14275. View

5.
Mayo-Wilson E, Imdad A, Junior J, Dean S, Bhutta Z . Preventive zinc supplementation for children, and the effect of additional iron: a systematic review and meta-analysis. BMJ Open. 2014; 4(6):e004647. PMC: 4067863. DOI: 10.1136/bmjopen-2013-004647. View