Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

Overview

Journal Transl Vis Sci Technol

Specialties Biomedical Engineering
Ophthalmology

Date 2021 May 18

PMID 34003982

Citations 19

Authors

Ying Kai Chan

Andrew D Dick

Sara Mary Hall

Thomas Langmann

Curtis L Scribner

Brian C Mansfield

Affiliations

Soon will be listed here.

Abstract

Subclinical or clinical inflammation often arises during ocular gene therapy with viral vectors. Understanding the biological bases and impacts on efficacy are important for clinical management and the improvement of future therapies.

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