Probiotic Supplement Preparation Relieves Test Anxiety by Regulating Intestinal Microbiota in College Students

Overview

Journal Dis Markers

Publisher Wiley

Specialty Biochemistry

Date 2021 May 13

PMID 33981369

Citations 11

Authors

Qi Qin

Hui Liu

Yulu Yang

Yifei Wang

Chaofei Xia

Puyuan Tian

Jing Wei

Shengjie Li

Tingtao Chen

Affiliations

Soon will be listed here.

Abstract

Test anxiety creates barriers to learning and performance, which further affects students' social, behavioural, and emotional development. Currently, the medication to treat test anxiety has not been reported yet. Here, we enrolled 120 students to evaluate the effect of probiotic supplement preparation (PSP) on test anxiety from the aspect of the intestinal microbiota. We found that the intake of PSP alleviated the symptoms of depression and anxiety in students with test anxiety by evaluating their mental state using the Hamilton Depression Rating Scale and Hamilton Anxiety Scale. High-throughput sequencing results indicated that the consumption of PSP increased the abundance of and that was lowered by the anxiety state in the intestinal microbiota of students. Meanwhile, taking PSP reduced the level of intestinal pathogens of and as well. In conclusion, our work shows that PSP can reduce test anxiety and restore the disturbed microbiota to the standard level in Chinese college students, rendering the use of PSP a promising strategy for test anxiety.

Citing Articles

Antibiotic-induced gut dysbiosis elicits gut-brain axis relevant multi-omic signatures and behavioral and neuroendocrine changes in a nonhuman primate model.

Hayer S, Conrin M, French J, Benson A, Alvarez S, Cooper K Gut Microbes. 2024; 16(1):2305476.

PMID: 38284649 PMC: 10826635. DOI: 10.1080/19490976.2024.2305476.

Modulation of Gut Microbiome Community Mitigates Multiple Sclerosis in a Mouse Model: The Promising Role of Alga as a Prebiotic.

Yousof S, Alghamdi B, Alqurashi T, Alam M, Tash R, Tanvir I Pharmaceuticals (Basel). 2023; 16(10).

PMID: 37895826 PMC: 10610500. DOI: 10.3390/ph16101355.

The brain-gut-microbiota axis in the treatment of neurologic and psychiatric disorders.

Naufel M, Truzzi G, Ferreira C, Coelho F Arq Neuropsiquiatr. 2023; 81(7):670-684.

PMID: 37402401 PMC: 10371417. DOI: 10.1055/s-0043-1767818.

Retracted: Probiotic Supplement Preparation Relieves Test Anxiety by Regulating Intestinal Microbiota in College Students.

Markers D Dis Markers. 2023; 2023:9806830.

PMID: 37387773 PMC: 10307291. DOI: 10.1155/2023/9806830.

Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options.

Kumar A, Pramanik J, Goyal N, Chauhan D, Sivamaruthi B, Prajapati B Pharmaceuticals (Basel). 2023; 16(4).

PMID: 37111321 PMC: 10146621. DOI: 10.3390/ph16040565.

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