The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy

Overview

Journal Cancer Cell

Publisher Cell Press

Specialty Oncology

Date 2018 Apr 11

PMID 29634945

Citations 627

Authors

Vancheswaran Gopalakrishnan

Beth A Helmink

Christine N Spencer

Alexandre Reuben

Jennifer A Wargo

Affiliations

Soon will be listed here.

Abstract

The microbiome is receiving significant attention given its influence on a host of human diseases including cancer. Its role in response to cancer treatment is becoming increasingly apparent, with evidence suggesting that modulating the gut microbiome may affect responses to numerous forms of cancer therapy. A working knowledge of the microbiome is vital as we move forward in this age of precision medicine, and an understanding of the microbiome's influence on immune responses and cancer is key. It is also important to understand factors influencing the gut microbiome and strategies to manipulate the microbiome to augment therapeutic responses.

Citing Articles

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