Phylogenetic Analysis of the Salinipostin γ-butyrolactone Gene Cluster Uncovers New Potential for Bacterial Signalling-molecule Diversity

Overview

Journal Microb Genom

Specialties Genetics
Microbiology

Date 2021 May 12

PMID 33979276

Citations 7

Authors

Kaitlin E Creamer

Yuta Kudo

Bradley S Moore

Paul R Jensen

Affiliations

Soon will be listed here.

Citing Articles

Identification of γ-butyrolactone signalling molecules in diverse actinomycetes using resin-assisted isolation and chemoenzymatic synthesis.

Kudo Y, Konoki K, Yotsu-Yamashita M RSC Chem Biol. 2025; .

PMID: 40046449 PMC: 11877004. DOI: 10.1039/d5cb00007f.

Structure elucidation, biosynthetic gene cluster distribution, and biological activities of ketomemicin analogs in .

Castro-Falcon G, Guillen-Matus D, Barbosa da Silva E, Guo W, Ross A, Serafim M bioRxiv. 2024; .

PMID: 39553956 PMC: 11565770. DOI: 10.1101/2024.10.29.620863.

NP MS Workflow: An Open-Source Software System to Empower Natural Product-Based Drug Discovery Using Untargeted Metabolomics.

Bazzano C, de Felicio R, Alves L, Costa J, Ortega R, Vieira B Anal Chem. 2024; 96(19):7460-7469.

PMID: 38702053 PMC: 11099897. DOI: 10.1021/acs.analchem.3c05829.

Small molecule inducers of actinobacteria natural product biosynthesis.

Alwali A, Parkinson E J Ind Microbiol Biotechnol. 2023; 50(1).

PMID: 37587009 PMC: 10549211. DOI: 10.1093/jimb/kuad019.

Synthesis of Gamma-Butyrolactone Hormones Enables Understanding of Natural Product Induction.

Wilbanks L, Hennigan H, Martinez-Brokaw C, Lakkis H, Thormann S, Eggly A ACS Chem Biol. 2023; 18(7):1624-1631.

PMID: 37338162 PMC: 10368014. DOI: 10.1021/acschembio.3c00241.

References

Alberti F, Leng D, Wilkening I, Song L, Tosin M, Corre C . Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chem Sci. 2019; 10(2):453-463. PMC: 6335953. DOI: 10.1039/c8sc03814g. View

Ceniceros A, Dijkhuizen L, Petrusma M . Molecular characterization of a Rhodococcus jostii RHA1 γ-butyrolactone(-like) signalling molecule and its main biosynthesis gene gblA. Sci Rep. 2017; 7(1):17743. PMC: 5735094. DOI: 10.1038/s41598-017-17853-6. View

Stamatakis A . RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. Bioinformatics. 2014; 30(9):1312-3. PMC: 3998144. DOI: 10.1093/bioinformatics/btu033. View

Hsiao N, Nakayama S, Merlo M, de Vries M, Bunet R, Kitani S . Analysis of two additional signaling molecules in Streptomyces coelicolor and the development of a butyrolactone-specific reporter system. Chem Biol. 2009; 16(9):951-60. DOI: 10.1016/j.chembiol.2009.08.010. View

Yamamoto S, He Y, Arakawa K, Kinashi H . Gamma-butyrolactone-dependent expression of the Streptomyces antibiotic regulatory protein gene srrY plays a central role in the regulatory cascade leading to lankacidin and lankamycin production in Streptomyces rochei. J Bacteriol. 2007; 190(4):1308-16. PMC: 2238197. DOI: 10.1128/JB.01383-07. View

Darriba D, Taboada G, Doallo R, Posada D . ProtTest 3: fast selection of best-fit models of protein evolution. Bioinformatics. 2011; 27(8):1164-5. PMC: 5215816. DOI: 10.1093/bioinformatics/btr088. View

Grafe U, Schade W, Eritt I, Fleck W, Radics L . A new inducer of anthracycline biosynthesis from Streptomyces viridochromogenes. J Antibiot (Tokyo). 1982; 35(12):1722-3. DOI: 10.7164/antibiotics.35.1722. View

Tan G, Peng Y, Lu C, Bai L, Zhong J . Engineering validamycin production by tandem deletion of γ-butyrolactone receptor genes in Streptomyces hygroscopicus 5008. Metab Eng. 2014; 28:74-81. DOI: 10.1016/j.ymben.2014.12.003. View

Kawachi R, Akashi T, Kamitani Y, Sy A, Wangchaisoonthorn U, Nihira T . Identification of an AfsA homologue (BarX) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis, virginiamycin biosynthesis and virginiamycin M1 resistance. Mol Microbiol. 2000; 36(2):302-13. DOI: 10.1046/j.1365-2958.2000.01819.x. View

10.

Millan-Aguinaga N, Chavarria K, Ugalde J, Letzel A, Rouse G, Jensen P . Phylogenomic Insight into Salinispora (Bacteria, Actinobacteria) Species Designations. Sci Rep. 2017; 7(1):3564. PMC: 5472633. DOI: 10.1038/s41598-017-02845-3. View

11.

Takano E . Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation. Curr Opin Microbiol. 2006; 9(3):287-94. DOI: 10.1016/j.mib.2006.04.003. View

12.

Mincer T, Fenical W, Jensen P . Culture-dependent and culture-independent diversity within the obligate marine actinomycete genus Salinispora. Appl Environ Microbiol. 2005; 71(11):7019-28. PMC: 1287694. DOI: 10.1128/AEM.71.11.7019-7028.2005. View

13.

Aroonsri A, Kitani S, Hashimoto J, Kosone I, Izumikawa M, Komatsu M . Pleiotropic control of secondary metabolism and morphological development by KsbC, a butyrolactone autoregulator receptor homologue in Kitasatospora setae. Appl Environ Microbiol. 2012; 78(22):8015-24. PMC: 3485943. DOI: 10.1128/AEM.02355-12. View

14.

Healy F, Eaton K, Limsirichai P, Aldrich J, Plowman A, King R . Characterization of gamma-butyrolactone autoregulatory signaling gene homologs in the angucyclinone polyketide WS5995B producer Streptomyces acidiscabies. J Bacteriol. 2009; 191(15):4786-97. PMC: 2715719. DOI: 10.1128/JB.00437-09. View

15.

Polkade A, Mantri S, Patwekar U, Jangid K . Quorum Sensing: An Under-Explored Phenomenon in the Phylum Actinobacteria. Front Microbiol. 2016; 7:131. PMC: 4748050. DOI: 10.3389/fmicb.2016.00131. View

16.

Zhu J, Sun D, Liu W, Chen Z, Li J, Wen Y . AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth. Mol Microbiol. 2016; 102(4):562-578. DOI: 10.1111/mmi.13479. View

17.

Ziemert N, Podell S, Penn K, Badger J, Allen E, Jensen P . The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity. PLoS One. 2012; 7(3):e34064. PMC: 3315503. DOI: 10.1371/journal.pone.0034064. View

18.

Arakawa K, Tsuda N, Taniguchi A, Kinashi H . The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. Chembiochem. 2012; 13(10):1447-57. DOI: 10.1002/cbic.201200149. View

19.

Niu G, Chater K, Tian Y, Zhang J, Tan H . Specialised metabolites regulating antibiotic biosynthesis in Streptomyces spp. FEMS Microbiol Rev. 2016; 40(4):554-73. DOI: 10.1093/femsre/fuw012. View

20.

Recio E, Colinas A, Rumbero A, Aparicio J, Martin J . PI factor, a novel type quorum-sensing inducer elicits pimaricin production in Streptomyces natalensis. J Biol Chem. 2004; 279(40):41586-93. DOI: 10.1074/jbc.M402340200. View