Imaging Approach to COVID-19 Associated Pulmonary Embolism

Overview

Journal Int J Clin Pract

Publisher Wiley

Specialty General Medicine

Date 2021 May 9

PMID 33966326

Citations 8

Authors

Lukas M Trunz

Patrick Lee

Steven M Lange

Corbin L Pomeranz

Laurence Needleman

Robert W Ford

Ajit Karambelkar

Baskaran Sundaram

Affiliations

Soon will be listed here.

Abstract

The novel coronavirus disease-2019 (COVID-19) illness and deaths, caused by the severe acute respiratory syndrome coronavirus-2, continue to increase. Multiple reports highlight the thromboembolic complications, such as pulmonary embolism (PE), in COVID-19. Imaging plays an essential role in the diagnosis and management of COVID-19 patients with PE. There continues to be a rapid evolution of knowledge related to COVID-19 associated PE. This review summarises the current understanding of prevalence, pathophysiology, role of diagnostic imaging modalities, and management, including catheter-directed therapy for COVID-19 associated PE. It also describes infection control considerations for the radiology department while providing care for patients with COVID-19 associated PE.

Citing Articles

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Niculae C, Hristea A, Albulescu A, Petre V, Anghel A, Damalan A Medicine (Baltimore). 2023; 102(27):e34250.

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References

Moore A, Wachsmann J, Chamarthy M, Panjikaran L, Tanabe Y, Rajiah P . Imaging of acute pulmonary embolism: an update. Cardiovasc Diagn Ther. 2018; 8(3):225-243. PMC: 6039809. DOI: 10.21037/cdt.2017.12.01. View

Schoepf U, Holzknecht N, Helmberger T, Crispin A, Hong C, Becker C . Subsegmental pulmonary emboli: improved detection with thin-collimation multi-detector row spiral CT. Radiology. 2002; 222(2):483-90. DOI: 10.1148/radiol.2222001802. View

Niu Y, Xian J, Lei Z, Liu X, Sun Q . Management of infection control and radiological protection in diagnostic radiology examination of COVID-19 cases. Radiat Med Prot. 2020; 1(2):75-80. PMC: 7274104. DOI: 10.1016/j.radmp.2020.05.005. View

Tang N, Bai H, Chen X, Gong J, Li D, Sun Z . Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020; 18(5):1094-1099. PMC: 9906401. DOI: 10.1111/jth.14817. View

England A, Littler E, Romani S, Cosson P . Modifications to mobile chest radiography technique during the COVID-19 pandemic - implications of X-raying through side room windows. Radiography (Lond). 2020; 27(1):193-199. PMC: 7396953. DOI: 10.1016/j.radi.2020.07.015. View

Abbas A, St Joseph E, Mansour O, Peebles C . Radiographic features of pulmonary embolism: Westermark and Palla signs. Postgrad Med J. 2014; 90(1065):422-3. DOI: 10.1136/postgradmedj-2013-132000. View

Wang X, Hu X, Tan W, Mazzone P, Mireles-Cabodevila E, Han X . Multicenter Study of Temporal Changes and Prognostic Value of a CT Visual Severity Score in Hospitalized Patients With Coronavirus Disease (COVID-19). AJR Am J Roentgenol. 2020; 217(1):83-92. DOI: 10.2214/AJR.20.24044. View

Wallace A, Albadawi H, Hoang P, Fleck A, Naidu S, Knuttinen G . Statins as a preventative therapy for venous thromboembolism. Cardiovasc Diagn Ther. 2018; 7(Suppl 3):S207-S218. PMC: 5778529. DOI: 10.21037/cdt.2017.09.12. View

Cozzi D, Albanesi M, Cavigli E, Moroni C, Bindi A, Luvara S . Chest X-ray in new Coronavirus Disease 2019 (COVID-19) infection: findings and correlation with clinical outcome. Radiol Med. 2020; 125(8):730-737. PMC: 7282464. DOI: 10.1007/s11547-020-01232-9. View

10.

Zuin M, Kuo W, Rigatelli G, Daggubati R, Vassiliev D, Roncon L . Catheter-directed therapy as a first-line treatment strategy in hemodynamically unstable patients with acute pulmonary embolism: Yes or no?. Int J Cardiol. 2016; 225:14-15. DOI: 10.1016/j.ijcard.2016.09.104. View

11.

Faggiano P, Bonelli A, Paris S, Milesi G, Bisegna S, Bernardi N . Acute pulmonary embolism in COVID-19 disease: Preliminary report on seven patients. Int J Cardiol. 2020; 313:129-131. PMC: 7250100. DOI: 10.1016/j.ijcard.2020.04.028. View

12.

Sheth S, Fetzer D, Frates M, Needleman L, Middleton W, Jones J . Guidelines for Ultrasound in the Radiology Department During the COVID-19 Pandemic. Ultrasound Q. 2020; 36(3):200-205. DOI: 10.1097/RUQ.0000000000000526. View

13.

Reeves R, Pomeranz C, Gomella A, Gulati A, Metra B, Hage A . Performance of a Severity Score on Admission Chest Radiography in Predicting Clinical Outcomes in Hospitalized Patients With Coronavirus Disease (COVID-19). AJR Am J Roentgenol. 2020; 217(3):623-632. DOI: 10.2214/AJR.20.24801. View

14.

Kearon C . Natural history of venous thromboembolism. Circulation. 2003; 107(23 Suppl 1):I22-30. DOI: 10.1161/01.CIR.0000078464.82671.78. View

15.

Goodacre S, Sampson F, Thomas S, Van Beek E, Sutton A . Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis. BMC Med Imaging. 2005; 5:6. PMC: 1262723. DOI: 10.1186/1471-2342-5-6. View

16.

Beckman M, Hooper W, Critchley S, Ortel T . Venous thromboembolism: a public health concern. Am J Prev Med. 2010; 38(4 Suppl):S495-501. DOI: 10.1016/j.amepre.2009.12.017. View

17.

Ren B, Yan F, Deng Z, Zhang S, Xiao L, Wu M . Extremely High Incidence of Lower Extremity Deep Venous Thrombosis in 48 Patients With Severe COVID-19 in Wuhan. Circulation. 2020; 142(2):181-183. DOI: 10.1161/CIRCULATIONAHA.120.047407. View

18.

Dua A, Thondapu V, Rosovsky R, Hunt D, Latz C, Waller H . Deep vein thrombosis protocol optimization to minimize healthcare worker exposure in coronavirus disease-2019. J Vasc Surg Venous Lymphat Disord. 2020; 9(2):299-306. PMC: 7418643. DOI: 10.1016/j.jvsv.2020.08.005. View

19.

Lu Y, Macapinlac H . Perfusion SPECT/CT to diagnose pulmonary embolism during COVID-19 pandemic. Eur J Nucl Med Mol Imaging. 2020; 47(9):2064-2065. PMC: 7205478. DOI: 10.1007/s00259-020-04851-6. View

20.

Guan W, Ni Z, Hu Y, Liang W, Ou C, He J . Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-1720. PMC: 7092819. DOI: 10.1056/NEJMoa2002032. View