Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients

Overview

Journal Rev Soc Bras Med Trop

Specialty Tropical Medicine

Date 2021 Apr 22

PMID 33886823

Citations 11

Authors

Denise Maria do Nascimento Costa

Maria Rosangela Cunha Duarte Coelho

Pedro Alves da Cruz Gouveia

Luan Araujo Bezerra

Claudia Diniz Lopes Marques

Angela Luzia Branco Pinto Duarte

Lucila Maria Valente

Vera Magalhaes

Affiliations

Soon will be listed here.

Abstract

The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection.

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