Malignant Monophasic Multiple Sclerosis or "Marburg's Disease"

Overview

Journal Neurology

Specialty Neurology

Date 1988 Jul 1

PMID 3386836

Citations 13

Authors

M F Mendez

S Pogacar

Affiliations

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Abstract

We report a patient with an acute monophasic demyelinating disease leading to death 29 days after onset. Neuroimaging showed progressive white matter attenuation, and neuropathology was characteristic of multiple sclerosis. Death in acute MS of the Marburg type may result from severe disseminated demyelination or involvement of critical brainstem structures.

Citing Articles

Death following rapidly progressive demyelinating disorder in a young female-a case report.

Wickramasinghe C, Fernando D, Wijetunge S, Sumanasekara H Forensic Sci Med Pathol. 2022; 19(1):86-90.

PMID: 36441477 DOI: 10.1007/s12024-022-00564-4.

Cyclophosphamide in highly aggressive Marburg-like multiple sclerosis.

Nicoletti T, Bianco A, Lucchini M, Gaudino S, Frisullo G, Mirabella M Ther Adv Neurol Disord. 2021; 14:17562864211050028.

PMID: 34659455 PMC: 8512236. DOI: 10.1177/17562864211050028.

14th EUNOS Congress: PORTO, PORTUGAL, 16-19 JUNE 2019.

Neuroophthalmology. 2019; 43(Suppl 1):1-221.

PMID: 31528195 PMC: 6736494. DOI: 10.1080/01658107.2019.1608780.

Fulminant multiple sclerosis (MS).

Rohani M, Ghourchian S Neurol Sci. 2011; 32(5):953-7.

PMID: 21863271 DOI: 10.1007/s10072-011-0723-0.

Long survival and clinical stability in Marburg's variant multiple sclerosis.

Turatti M, Gajofatto A, Rossi F, Vedovello M, Benedetti M Neurol Sci. 2010; 31(6):807-11.

PMID: 20461429 DOI: 10.1007/s10072-010-0287-4.