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» Articles » PMID: 2266377

Fulminant Monophasic Multiple Sclerosis, Marburg's Type

Overview
Journal J Neurol Neurosurg Psychiatry
Publisher BMJ Publishing Group
Specialties Neurology
Neurosurgery
Psychiatry
Date 1990 Oct 1
PMID 2266377
Citations 21
Authors
M D Johnson
P Lavin
W O Whetsell Jr
Affiliations
Soon will be listed here.
Abstract

The clinical, neuroradiological and necropsy findings are described in a 49 year old woman with long-standing idiopathic pulmonary haemosiderosis and acute monophasic multiple sclerosis (Marburg's type). Progression of the demyelinating process produced blindness and paraplegia over three weeks. At five weeks, magnetic reasonance imaging (MRI) studies showed lesions in the pons and left occipital lobe. The patient died 10 weeks after onset of symptoms. Necropsy examination revealed acute plaques in the optic chiasm, and the white matter around the lateral and fourth ventricle and spinal cord. Similarities between this and previously described cases of Marburg's disease are discussed.

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References
1.
Troiano R, Cook S, Dowling P . Steroid therapy in multiple sclerosis. Point of view. Arch Neurol. 1987; 44(8):803-7. DOI: 10.1001/archneur.1987.00520200007008. View
2.
. Acute central nervous system disorder mimicking stroke. Med J Aust. 1981; 1(3):136-8. DOI: 10.5694/j.1326-5377.1981.tb135386.x. View
3.
Lassmann H, Budka H, Schnaberth G . Inflammatory demyelinating polyradiculitis in a patient with multiple sclerosis. Arch Neurol. 1981; 38(2):99-102. DOI: 10.1001/archneur.1981.00510020057008. View
4.
STERNBERGER L, HARDY Jr P, CUCULIS J, MEYER H . The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. J Histochem Cytochem. 1970; 18(5):315-33. DOI: 10.1177/18.5.315. View
5.
Banerjee A, Chopra J, Kumar B . Acute multiple sclerosis - report of a case with neuropathological and neurochemical studies. Neurol India. 1977; 25(4):233-7. View