Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2021 Apr 3

PMID 33803502

Citations 16

Authors

Seyedeh Maryam Hosseinikhah

Mahmood Barani

Abbas Rahdar

Henning Madry

Rabia Arshad

Vahideh Mohammadzadeh

Magali Cucchiarini

Affiliations

Soon will be listed here.

Abstract

Nanomaterials have received increasing attention due to their unique chemical and physical properties for the treatment of rheumatoid arthritis (RA), the most common complex multifactorial joint-associated autoimmune inflammatory disorder. RA is characterized by an inflammation of the synovium with increased production of proinflammatory cytokines (IL-1, IL-6, IL-8, and IL-10) and by the destruction of the articular cartilage and bone, and it is associated with the development of cardiovascular disorders such as heart attack and stroke. While a number of imaging tools allow for the monitoring and diagnosis of inflammatory arthritis, and despite ongoing work to enhance their sensitivity and precision, the proper assessment of RA remains difficult particularly in the early stages of the disease. Our goal here is to describe the benefits of applying various nanomaterials as next-generation RA imaging and detection tools using contrast agents and nanosensors and as improved drug delivery systems for the effective treatment of the disease.

Citing Articles

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Nano - Based Therapeutic Strategies in Management of Rheumatoid Arthritis.

Nautiyal G, Sharma S, Kaushik D, Pandey P Recent Pat Nanotechnol. 2023; 18(4):433-456.

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Receptors expressions on peripheral lymphocytes and CD4 CD183 as a diagnostics biomarker for rheumatoid arthritis: A case-control study in Ghana.

Sakyi S, Buckman T, Yeboah-Mensah K, Senu E, Effah A, Antwi-Berko D Immun Inflamm Dis. 2023; 11(8):e976.

PMID: 37647423 PMC: 10465995. DOI: 10.1002/iid3.976.

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