» Articles » PMID: 33802041

Bioprospecting Fluorescent Plant Growth Regulators from Arabidopsis to Vegetable Crops

Overview
Journal Int J Mol Sci
Publisher MDPI
Date 2021 Apr 3
PMID 33802041
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

The phytohormone auxin is involved in almost every process of a plant's life, from germination to plant development. Nowadays, auxin research connects synthetic chemistry, plant biology and computational chemistry in order to develop innovative and safe compounds to be used in sustainable agricultural practice. In this framework, we developed new fluorescent compounds, ethanolammonium -aminobenzoate (HEA-ABA) and -nitrobenzoate (HEA-NBA), and investigated their auxin-like behavior on two main commercial vegetables cultivated in Europe, cucumber () and tomato (), in comparison to the model plant Arabidopsis (). Moreover, the binding modes and affinities of two organic salts in relation to the natural auxin indole-3-acetic acid (IAA) into TIR1 auxin receptor were investigated by computational approaches (homology modeling and molecular docking). Both experimental and theoretical results highlight HEA-ABA as a fluorescent compound with auxin-like activity both in Arabidopsis and the commercial cucumber and tomato. Therefore, alkanolammonium benzoates have a great potential as promising sustainable plant growth stimulators to be efficiently used in vegetable crops.

Citing Articles

Arabidopsis Root Development Regulation by the Endogenous Folate Precursor, Para-Aminobenzoic Acid, via Modulation of the Root Cell Cycle.

Lasok H, Nziengui H, Kochersperger P, Ditengou F Plants (Basel). 2023; 12(24).

PMID: 38140403 PMC: 10748309. DOI: 10.3390/plants12244076.

References
1.
Halgren T . Identifying and characterizing binding sites and assessing druggability. J Chem Inf Model. 2009; 49(2):377-89. DOI: 10.1021/ci800324m. View

2.
Sastry G, Adzhigirey M, Day T, Annabhimoju R, Sherman W . Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments. J Comput Aided Mol Des. 2013; 27(3):221-34. DOI: 10.1007/s10822-013-9644-8. View

3.
Ivanchenko M, Napsucialy-Mendivil S, Dubrovsky J . Auxin-induced inhibition of lateral root initiation contributes to root system shaping in Arabidopsis thaliana. Plant J. 2010; 64(5):740-52. DOI: 10.1111/j.1365-313X.2010.04365.x. View

4.
Emenecker R, Strader L . Auxin-Abscisic Acid Interactions in Plant Growth and Development. Biomolecules. 2020; 10(2). PMC: 7072425. DOI: 10.3390/biom10020281. View

5.
Friesner R, Banks J, Murphy R, Halgren T, Klicic J, Mainz D . Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. J Med Chem. 2004; 47(7):1739-49. DOI: 10.1021/jm0306430. View