Circulating Tumor Cells for Glioma

Overview

Journal Front Oncol

Specialty Oncology

Date 2021 Mar 29

PMID 33777749

Citations 19

Authors

Huikai Zhang

Fanen Yuan

Yangzhi Qi

Baohui Liu

Qianxue Chen

Affiliations

Soon will be listed here.

Abstract

Liquid biopsy has entered clinical applications for several cancers, including metastatic breast, prostate, and colorectal cancer for CTC enumeration and NSCLC for EGFR mutations in ctDNA, and has improved the individualized treatment of many cancers, but relatively little progress has been made in validating circulating biomarkers for brain malignancies. So far, data on circulating tumor cells about glioma are limited, the application of circulating tumor cells as biomarker for glioma patients has only just begun. This article reviews the research status and application prospects of circulating tumor cells in gliomas. Several detection methods and research results of circulating tumor cells about clinical research in gliomas are briefly discussed. The wide application prospect of circulating tumor cells in glioma deserves further exploration, and the research on more sensitive and convenient detection methods is necessary.

Citing Articles

Circulating biomarkers in high-grade gliomas: current insights and future perspectives.

Taori S, Habib A, Adida S, Gecici N, Sharma N, Calcaterra M J Neurooncol. 2024; 172(1):41-49.

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Potential of sonobiopsy as a novel diagnosis tool for brain cancer.

Yan L, Fu K, Li L, Li Q, Zhou X Mol Ther Oncol. 2024; 32(3):200840.

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Detection of PD‑L1 expression and epithelial‑mesenchymal transition of circulating tumor cells in non‑small cell lung cancer.

Jiang J, Mo W, Lian X, Cao D, Cheng H, Wang H Exp Ther Med. 2024; 28(1):294.

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Clinical applications of cerebrospinal fluid liquid biopsies in central nervous system tumors.

Diaz M, Chudsky S, Pentsova E, Miller A Transl Oncol. 2024; 41:101881.

PMID: 38218027 PMC: 10825768. DOI: 10.1016/j.tranon.2024.101881.

Liquid biopsy: creating opportunities in brain space.

Trivedi R, Bhat K Br J Cancer. 2023; 129(11):1727-1746.

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