A Visible-Light Promoted Amine Oxidation Catalyzed by a Cp*Ir Complex

Overview

Journal ChemCatChem

Date 2021 Mar 29

PMID 33777249

Citations 1

Authors

Holly Jane Davis

Daniel Haussinger

Thomas R Ward

Yasunori Okamoto

Affiliations

Soon will be listed here.

Abstract

Through a rapid screening of Cp*Ir complexes based on a turn-on type fluorescence readout, a [Cp*Ir(dipyrido[3,2-a : 2',3'-c]phenazine)Cl] complex was found to catalyze the blue-light promoted dehydrogenation of -heterocycles under physiological conditions. In the dehydrogenation of tetrahydroisoquinolines, the catalyst preferentially yielded the monodehydrogenated product, accompanying HO generation. We surmise that this mechanism may be reminiscent of flavin-dependent oxidases.

Citing Articles

A Visible-Light Promoted Amine Oxidation Catalyzed by a Cp*Ir Complex.

Davis H, Haussinger D, Ward T, Okamoto Y ChemCatChem. 2021; 12(18):4512-4516.

PMID: 33777249 PMC: 7984327. DOI: 10.1002/cctc.202000488.

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