Association of Dyslipidaemia with Osteoporosis in Postmenopausal Women

Overview

Journal J Int Med Res

Publisher Sage Publications

Specialty General Medicine

Date 2021 Mar 29

PMID 33775162

Citations 9

Authors

Lingnan Zhang

Qilong Liu

Xianshang Zeng

Wenshan Gao

Yanan Niu

Xiaoyong Ma

Huijun Xie

Xiaozhe Zhou

Weiguang Yu

Guixing Xu

Affiliations

Soon will be listed here.

Abstract

Objective: To assess the association of dyslipidaemia with osteoporosis in postmenopausal women.

Methods: Data from 160 postmenopausal women with newly diagnosed osteoporosis (osteoporosis group) and 156 healthy controls (control group) were retrospectively reviewed from 2016 to 2020. The primary outcomes were laboratory values assessed by a multivariate binary logistic regression model.

Results: Factors that greatly increased the risk of being in the osteoporosis group included high low-density lipoprotein (LDL) and low high-density lipoprotein (HDL) levels. The osteoporosis group had lower HDL and higher LDL levels than the control group. A multivariate binary logistic regression model showed that lower HDL and higher LDL levels were the only variables that were significantly associated with osteoporosis (odds ratio 1.86, 95% confidence interval: 3.66-4.25 and odds ratio 1.47, 95% confidence interval: 1.25-2.74, respectively).

Conclusion: Low HDL and high LDL levels may be associated with the occurrence of osteoporosis in postmenopausal women.

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