» Articles » PMID: 33770498

Stem Cell-based Models of Embryos: The Need for Improved Naming Conventions

Overview
Publisher Cell Press
Specialty Cell Biology
Date 2021 Mar 26
PMID 33770498
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Stem cell-based models of embryos are known by various names, with different naming conventions, leading to confusion regarding their composition and potential. We propose the need for a general term for the field to promote public engagement and the development of a systematic nomenclature system to differentiate between specific models.

Citing Articles

In Vitro Models of Cardiovascular Disease: Embryoid Bodies, Organoids and Everything in Between.

Stougiannou T, Christodoulou K, Karangelis D Biomedicines. 2025; 12(12.

PMID: 39767621 PMC: 11726960. DOI: 10.3390/biomedicines12122714.


Current Status of Synthetic Mammalian Embryo Models.

Kim H, Kim E Int J Mol Sci. 2024; 25(23.

PMID: 39684574 PMC: 11641582. DOI: 10.3390/ijms252312862.


Ethical, legal, regulatory, and policy issues concerning embryoids: a systematic review of the literature.

Iltis A, Koster G, Reeves E, Matthews K Stem Cell Res Ther. 2023; 14(1):209.

PMID: 37605210 PMC: 10441753. DOI: 10.1186/s13287-023-03448-8.


Regeneration of the human segmentation clock in somitoids in vitro.

Qin Y, Huang X, Cai Z, Cai B, He J, Yao Y EMBO J. 2022; 41(23):e110928.

PMID: 36245268 PMC: 9713707. DOI: 10.15252/embj.2022110928.


Sculpting with stem cells: how models of embryo development take shape.

Veenvliet J, Lenne P, Turner D, Nachman I, Trivedi V Development. 2021; 148(24).

PMID: 34908102 PMC: 8722391. DOI: 10.1242/dev.192914.


References
1.
Warmflash A . Synthetic Embryos: Windows into Mammalian Development. Cell Stem Cell. 2017; 20(5):581-582. DOI: 10.1016/j.stem.2017.04.001. View

2.
van den Brink S, Baillie-Johnson P, Balayo T, Hadjantonakis A, Nowotschin S, Turner D . Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells. Development. 2014; 141(22):4231-42. PMC: 4302915. DOI: 10.1242/dev.113001. View

3.
Martyn I, Brivanlou A, Siggia E . A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells. Development. 2019; 146(6). PMC: 6451321. DOI: 10.1242/dev.172791. View

4.
Purnell B, Lavine M . Approximating organs. Science. 2019; 364(6444):946-947. DOI: 10.1126/science.aay1351. View

5.
Moris N, Anlas K, van den Brink S, Alemany A, Schroder J, Ghimire S . An in vitro model of early anteroposterior organization during human development. Nature. 2020; 582(7812):410-415. DOI: 10.1038/s41586-020-2383-9. View