Clinical Characteristics and Factors Associated with Triple Therapy Use in Newly Diagnosed Patients with COPD

Overview

Journal NPJ Prim Care Respir Med

Specialties Public Health
Pulmonary Medicine

Date 2021 Mar 23

PMID 33753747

Citations 7

Authors

Monica Monteagudo

Miriam Barrecheguren

Iryna Solntseva

Nafeesa Dhalwani

Alison Booth

Alexa Nunez

Dimitra Lambrelli

Marc Miravitlles

Affiliations

Soon will be listed here.

Abstract

There is limited information about the initiation of triple therapy (TT) in patients with chronic obstructive pulmonary disease (COPD) in primary care. This was an observational, population-based study in patients identified from a primary care electronic medical records database in Catalonia from 2011 to 2015 aimed to identify the use of TT in patients with newly diagnosed COPD. A total of 69,668 newly diagnosed patients were identified of whom 11,524 (16.5%) initiated TT, of whom 8626 initiated TT at or immediately after COPD diagnosis. Among them, 72.3% were GOLD A/B, 14.6% were frequent exacerbators, and 7.1% had asthma-COPD overlap (ACO). Variables associated with TT initiation were: male sex, older age, previous exacerbations, ACO, a previous treatment regimen containing an inhaled corticosteroid, previous pneumonia, and history of lung cancer. A significant number of COPD patients in Primary Care initiated TT shortly after or even before an established COPD diagnosis.

Citing Articles

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Characteristics and treatment patterns of patients with asthma on multiple-inhaler triple therapy in Spain.

Barrecheguren M, Monteagudo M, Miravitlles M, Flor X, Nunez A, Osorio J NPJ Prim Care Respir Med. 2022; 32(1):11.

PMID: 35273167 PMC: 8913688. DOI: 10.1038/s41533-022-00270-2.

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