» Articles » PMID: 28883469

Characteristics of Newly Diagnosed COPD Patients Treated with Triple Inhaled Therapy by General Practitioners: a Real World Italian Study

Overview
Date 2017 Sep 9
PMID 28883469
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

Chronic Lung Disease: ENSURING CORRECT PRESCRIPTIONS FOR EARLY-STAGE DISEASE: An improved education program for doctors promoting correct use of medication for chronic lung disease is needed in Italy. Current guidelines state that inhaled corticosteroids (ICSs) should be reserved for patients with severe chronic obstructive pulmonary disease (COPD), but it appears that doctors do not always follow this advice. Fabiano Di Marco, at San Paolo Hospital-Università degli Studi di Milano, and co-workers analyzed data from 32,046 COPD patients newly-diagnosed by family doctors in Italy between 2010 and 2013. When the researchers followed up on patients after 1 year, 2028 (6.3%) of newly-diagnosed patients were being treated with triple inhaled therapy incorporating ICSs-42% of these patients had started triple therapy immediately upon diagnosis. Being an older male and having been prescribed with a ICS/LABA FDC at diagnosis were strong predictors of triple therapy use within 1 year from the diagnosis.

Citing Articles

Clinical characteristics, use and switch of drugs for obstructive airway diseases among patients with COPD experiencing an exacerbation: a retrospective analysis of Italian administrative healthcare data.

Dondi L, Ronconi G, Calabria S, DellAnno I, Dondi L, Piccinni C BMC Pulm Med. 2024; 24(1):525.

PMID: 39438812 PMC: 11494943. DOI: 10.1186/s12890-024-03339-5.


Description and management of patients with anal fissure: insights on Italian primary care setting coming from real-world data.

Gallo G, Pegoraro V, Trompetto M Updates Surg. 2024; 76(6):2193-2203.

PMID: 38796820 PMC: 11541248. DOI: 10.1007/s13304-024-01882-8.


Acute treatment of migraine: quantifying the unmet need through real-world data in Italy.

Sacco S, Di Ciaccio S, Di Virgilio R, Pegoraro V, Ornello R Neurol Sci. 2024; 45(9):4427-4435.

PMID: 38538924 PMC: 11306385. DOI: 10.1007/s10072-024-07493-w.


Pharmacotherapies in Older Adults with COPD: Challenges and Opportunities.

Matera M, Hanania N, Maniscalco M, Cazzola M Drugs Aging. 2023; 40(7):605-619.

PMID: 37316689 PMC: 10300166. DOI: 10.1007/s40266-023-01038-0.


Beyond Dual Bronchodilation - Triple Therapy, When and Why.

Cazzola M, Rogliani P, Laitano R, Calzetta L, Matera M Int J Chron Obstruct Pulmon Dis. 2022; 17:165-180.

PMID: 35068929 PMC: 8766250. DOI: 10.2147/COPD.S345263.


References
1.
Taylor A, Price K, Gill T, Adams R, Pilkington R, Carrangis N . Multimorbidity - not just an older person's issue. Results from an Australian biomedical study. BMC Public Health. 2010; 10:718. PMC: 3001730. DOI: 10.1186/1471-2458-10-718. View

2.
Avanzini F, Marzona I, Baviera M, Barlera S, Milani V, Caimi V . Improving cardiovascular prevention in general practice: Results of a comprehensive personalized strategy in subjects at high risk. Eur J Prev Cardiol. 2015; 23(9):947-55. DOI: 10.1177/2047487315613664. View

3.
Wurst K, Punekar Y, Shukla A . Treatment evolution after COPD diagnosis in the UK primary care setting. PLoS One. 2014; 9(9):e105296. PMC: 4152013. DOI: 10.1371/journal.pone.0105296. View

4.
Osthoff M, Jenkins C, Leuppi J . Chronic obstructive pulmonary disease--a treatable disease. Swiss Med Wkly. 2013; 143:w13777. DOI: 10.4414/smw.2013.13777. View

5.
Montuschi P, Ciabattoni G . Bronchodilating drugs for chronic obstructive pulmonary disease: current status and future trends. J Med Chem. 2015; 58(10):4131-64. DOI: 10.1021/jm5013227. View