Role of Biomaterials in the Diagnosis, Prevention, Treatment, and Study of Corona Virus Disease 2019 (COVID-19)

Overview

Journal Emergent Mater

Date 2021 Mar 22

PMID 33748672

Citations 11

Authors

Yavuz Nuri Ertas

Mahboobeh Mahmoodi

Fahimeh Shahabipour

Vahid Jahed

Sibel Emir Diltemiz

Rumeysa Tutar

Nureddin Ashammakhi

Affiliations

Soon will be listed here.

Abstract

Recently emerged novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting corona virus disease 2019 (COVID-19) led to urgent search for methods to prevent and treat COVID-19. Among important disciplines that were mobilized is the biomaterials science and engineering. Biomaterials offer a range of possibilities to develop disease models, protective, diagnostic, therapeutic, monitoring measures, and vaccines. Among the most important contributions made so far from this field are tissue engineering, organoids, and organ-on-a-chip systems, which have been the important frontiers in developing tissue models for viral infection studies. Also, due to low bioavailability and limited circulation time of conventional antiviral drugs, controlled and targeted drug delivery could be applied alternatively. Fortunately, at the time of writing this paper, we have two successful vaccines and new at-home detection platforms. In this paper, we aim to review recent advances of biomaterial-based platforms for protection, diagnosis, vaccination, therapeutics, and monitoring of SARS-CoV-2 and discuss challenges and possible future research directions in this field.

Citing Articles

Research Progress on the Application of Natural Medicines in Biomaterial Coatings.

Wang Y, Duan H, Zhang Z, Chen L, Li J Materials (Basel). 2024; 17(22).

PMID: 39597430 PMC: 11595593. DOI: 10.3390/ma17225607.

T Cell and Natural Killer Cell Membrane-Camouflaged Nanoparticles for Cancer and Viral Therapies.

Ozsoy F, Mohammed M, Jan N, Lulek E, Ertas Y ACS Appl Bio Mater. 2024; 7(5):2637-2659.

PMID: 38687958 PMC: 11110059. DOI: 10.1021/acsabm.4c00074.

USE OF ARTIFICIAL CELLS AS DRUG CARRIERS.

Diltemiz S, Tavafoghi PhD M, de Barros N, Kanada M, Heinamaki J, Contag C Mater Chem Front. 2024; 5(18):6672-6692.

PMID: 38344270 PMC: 10857888. DOI: 10.1039/d1qm00717c.

Biomedical equipments, vaccine and drug in the prevention, diagnosis and treatment of COVID-19.

Zhang L Heliyon. 2023; 9(7):e18089.

PMID: 37483808 PMC: 10362228. DOI: 10.1016/j.heliyon.2023.e18089.

Blood filtering system for COVID-19 management: novel modality of the cytokine storm therapeutics.

Chavda V, Raval N, Sheta S, Vora L, Elrashdy F, Redwan E Front Immunol. 2023; 14:1064459.

PMID: 37153613 PMC: 10160615. DOI: 10.3389/fimmu.2023.1064459.

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