Second Primary Pleomorphic Carcinoma Arising from the Pneumonectomy Cavity of Non-small Cell Lung Cancer: A Case Report

Overview

Journal Respir Med Case Rep

Date 2021 Mar 18

PMID 33732613

Authors

Chaiyoung Lee

Byeong-Ho Jeong

Kyungjong Lee

Jae Il Zo

Jong-Mu Sun

Yoon-La Choi

Hojoong Kim

Affiliations

Soon will be listed here.

Abstract

Here, we report a thirteen years' survivor of initial primary lung cancer, who successfully diagnosed with second primary lung cancer(SPLC). It was arising from the pneumonectomy cavity of a non-small cell lung cancer(NSCLC). Few cases of SPLC associated with the post-pneumonectomy cavity have been reported in the literature. The histologic results of SPLC was metastatic pleomorphic carcinoma. It is a rare type of lung cancer; which incidence has been reported to range from 0.1% to 0.4% among all lung cancers. Based on regular follow-up with chest computed tomography(CT) and an understanding of post-pneumonectomy changes, the second primary pleomorphic carcinoma was correctly diagnosed and appropriately treated.

References

Aberle D, Adams A, Berg C, Black W, Clapp J, Fagerstrom R . Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365(5):395-409. PMC: 4356534. DOI: 10.1056/NEJMoa1102873. View

Mayne N, Mallipeddi M, Darling A, Yang C, Eltaraboulsi W, Shoffner A . Impact of Surveillance After Lobectomy for Lung Cancer on Disease Detection and Survival. Clin Lung Cancer. 2020; 21(5):407-414. DOI: 10.1016/j.cllc.2020.03.011. View

Oikawa T, Ohira T, Matsubayashi J, Konaka C, Ikeda N . Factors Influencing the Diagnostic Accuracy of Identifying the Histologic Type of Non--Small-Lung Cancer With Small Samples. Clin Lung Cancer. 2015; 16(5):374-8. DOI: 10.1016/j.cllc.2015.03.007. View

Watanabe S, Asamura H, Suzuki K, Tsuchiya R . Recent results of postoperative mortality for surgical resections in lung cancer. Ann Thorac Surg. 2004; 78(3):999-1002. DOI: 10.1016/j.athoracsur.2004.04.007. View

Tsukada G, Stark P . Postpneumonectomy complications. AJR Am J Roentgenol. 1997; 169(5):1363-70. DOI: 10.2214/ajr.169.5.9353460. View

Rubins J, Unger M, Colice G . Follow-up and surveillance of the lung cancer patient following curative intent therapy: ACCP evidence-based clinical practice guideline (2nd edition). Chest. 2007; 132(3 Suppl):355S-367S. DOI: 10.1378/chest.07-1390. View

. Lung Cancer Incidence and Mortality with Extended Follow-up in the National Lung Screening Trial. J Thorac Oncol. 2019; 14(10):1732-1742. PMC: 6764895. DOI: 10.1016/j.jtho.2019.05.044. View

Han S, Rivera G, Tammemagi M, Plevritis S, Gomez S, Cheng I . Risk Stratification for Second Primary Lung Cancer. J Clin Oncol. 2017; 35(25):2893-2899. PMC: 5946715. DOI: 10.1200/JCO.2017.72.4203. View

Rossi G, Cavazza A, Sturm N, Migaldi M, Facciolongo N, Longo L . Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: a clinicopathologic and immunohistochemical study of 75 cases. Am J Surg Pathol. 2003; 27(3):311-24. DOI: 10.1097/00000478-200303000-00004. View

10.

CATTANEO S, KLASSEN K . Letter: Carcinoma of the chest wall complicating chronically draining empyema. Chest. 1973; 64(5):673-4. DOI: 10.1378/chest.64.5.673-a. View

11.

Martini N, Melamed M . Multiple primary lung cancers. J Thorac Cardiovasc Surg. 1975; 70(4):606-12. View

12.

Deschamps C, Pairolero P, Trastek V, Payne W . Multiple primary lung cancers. Results of surgical treatment. J Thorac Cardiovasc Surg. 1990; 99(5):769-77; discussion 777-8. View

13.

Pfister D, Johnson D, Azzoli C, Sause W, Smith T, Baker Jr S . American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol. 2003; 22(2):330-53. DOI: 10.1200/JCO.2004.09.053. View

14.

Travis W, Brambilla E, Nicholson A, Yatabe Y, Austin J, Beasley M . The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol. 2015; 10(9):1243-1260. DOI: 10.1097/JTO.0000000000000630. View

15.

Chang Y, Lee Y, Shih J, Wu C . Pulmonary pleomorphic (spindle) cell carcinoma: peculiar clinicopathologic manifestations different from ordinary non-small cell carcinoma. Lung Cancer. 2001; 34(1):91-7. DOI: 10.1016/s0169-5002(01)00224-0. View

16.

Wood D . National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines for Lung Cancer Screening. Thorac Surg Clin. 2015; 25(2):185-97. DOI: 10.1016/j.thorsurg.2014.12.003. View

17.

Fishback N, Travis W, Moran C, Guinee Jr D, McCarthy W, Koss M . Pleomorphic (spindle/giant cell) carcinoma of the lung. A clinicopathologic correlation of 78 cases. Cancer. 1994; 73(12):2936-45. DOI: 10.1002/1097-0142(19940615)73:12<2936::aid-cncr2820731210>3.0.co;2-u. View

18.

DEATON Jr W . Carcinoma arising in chronic empyema cavity. Case report with review of the literature. Dis Chest. 1962; 42:563-6. DOI: 10.1378/chest.42.5.563. View

19.

Kopec S, IRWIN R, BALIKIAN J, Conlan A . The postpneumonectomy state. Chest. 1998; 114(4):1158-84. DOI: 10.1378/chest.114.4.1158. View

20.

Martini N, Bains M, Burt M, Zakowski M, McCormack P, Rusch V . Incidence of local recurrence and second primary tumors in resected stage I lung cancer. J Thorac Cardiovasc Surg. 1995; 109(1):120-9. DOI: 10.1016/S0022-5223(95)70427-2. View