Factors Influencing the Immunogenicity of Influenza Vaccines

Overview

Journal Hum Vaccin Immunother

Specialty Allergy & Immunology

Date 2021 Mar 11

PMID 33705263

Citations 12

Authors

Simin Wen

Zhengyu Wu

Shuyi Zhong

Mao Li

Yuelong Shu

Affiliations

Soon will be listed here.

Abstract

Annual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect the immunogenicity of the vaccines to provide best protection for vaccine recipients. This paper reviews the factors that may influence the immunogenicity of influenza vaccines from the aspects of vaccine factors, adjuvants, individual factors, repeated vaccination, and genetic factors. The confirmed or hypothesized molecular mechanisms of these factors have also been briefly summarized.

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