» Articles » PMID: 33672537

Health Benefits of Antioxidative Peptides Derived from Legume Proteins with a High Amino Acid Score

Overview
Date 2021 Mar 6
PMID 33672537
Citations 29
Authors
Affiliations
Soon will be listed here.
Abstract

Legumes such as soybean, chickpea, lentil, cowpea, and mung bean, are valuable sources of protein with a high amino acid score and can provide bioactive peptides. This manuscript presents a review on legume-derived peptides, focusing on in vitro and in vivo studies on the potential antioxidative activities of protein hydrolysates and their characterization, amino acid sequences, or purified/novel peptides. The health implications of legume-derived antioxidative peptides in reducing the risks of cancer and cardiovascular diseases are linked with their potent action against oxidation and inflammation. The molecular weight profiles and amino acid sequences of purified and characterized legume-derived antioxidant peptides are not well established. Therefore, further exploration of legume protein hydrolysates is necessary for assessing the potential applications of antioxidant-derived peptides in the functional food industry.

Citing Articles

Mung Bean Functional Protein Enhances Endothelial Function via Antioxidant Activity and Inflammation Modulation in Middle-Aged Adults: A Randomized Double-Blind Trial.

Muchimapura S, Thukhammee W, Phuthong S, Potue P, Khamseekaew J, Tong-Un T Foods. 2024; 13(21).

PMID: 39517211 PMC: 11544986. DOI: 10.3390/foods13213427.


Insight into the interaction between amino acids and SO: Detailed bonding modes.

Yang Y, Yu J, Jiang X, Lai K, Miao J J Mol Model. 2024; 30(8):291.

PMID: 39073631 DOI: 10.1007/s00894-024-06083-z.


Effect of Bioactive Peptides on Gut Microbiota and Their Relations to Human Health.

Wijesekara T, Abeyrathne E, Ahn D Foods. 2024; 13(12).

PMID: 38928795 PMC: 11202804. DOI: 10.3390/foods13121853.


A Review of Bioactive Compound Effects from Primary Legume Protein Sources in Human and Animal Health.

Shea Z, Ogando do Granja M, Fletcher E, Zheng Y, Bewick P, Wang Z Curr Issues Mol Biol. 2024; 46(5):4203-4233.

PMID: 38785525 PMC: 11120442. DOI: 10.3390/cimb46050257.


Nutritional Potential of Adzuki Bean Germplasm and Mining Nutri-Dense Accessions through Multivariate Analysis.

D D, Padhi S, Gore P, Tripathi K, Katral A, Chandora R Foods. 2023; 12(22).

PMID: 38002217 PMC: 10670495. DOI: 10.3390/foods12224159.


References
1.
Lourenco S, Moldao-Martins M, Alves V . Antioxidants of Natural Plant Origins: From Sources to Food Industry Applications. Molecules. 2019; 24(22). PMC: 6891691. DOI: 10.3390/molecules24224132. View

2.
Kusumah J, Real Hernandez L, Gonzalez de Mejia E . Antioxidant Potential of Mung Bean () Albumin Peptides Produced by Enzymatic Hydrolysis Analyzed by Biochemical and In Silico Methods. Foods. 2020; 9(9). PMC: 7554906. DOI: 10.3390/foods9091241. View

3.
Garcia-Mora P, Penas E, Frias J, Gomez R, Martinez-Villaluenga C . High-pressure improves enzymatic proteolysis and the release of peptides with angiotensin I converting enzyme inhibitory and antioxidant activities from lentil proteins. Food Chem. 2014; 171:224-32. DOI: 10.1016/j.foodchem.2014.08.116. View

4.
Marcela G, Eva R, Del Carmen R, Rosalva M . Evaluation of the Antioxidant and Antiproliferative Effects of Three Peptide Fractions of Germinated Soybeans on Breast and Cervical Cancer Cell Lines. Plant Foods Hum Nutr. 2016; 71(4):368-374. DOI: 10.1007/s11130-016-0568-z. View

5.
Evcan E, Gulec S . The development of lentil derived protein-iron complexes and their effects on iron deficiency anemia in vitro. Food Funct. 2020; 11(5):4185-4192. DOI: 10.1039/d0fo00384k. View