Normative Dataset for Plasma Cytokines in Healthy Human Adults

Overview

Journal Data Brief

Date 2021 Mar 5

PMID 33665253

Citations 10

Authors

Yingkai Li

John S Yi

Melissa A Russo

Marilyn Rosa-Bray

Kent J Weinhold

Jeffrey T Guptill

Affiliations

Soon will be listed here.

Abstract

We determined normative data for plasma cytokines established from a cohort of 126 carefully screened healthy adults aged 18 to 64 years. Participants were enrolled to ensure an even age and sex distribution and to include at least 30% non-Caucasians. Plasma cytokines for 18 analytes were tested by multiplex immunoassay. The data are presented by age cohort (18-29 years, 30-39, 40-49, and 50-66), as well as by sex and racial background. This dataset complements published normative ranges of cellular subsets generated by comprehensive polychromatic flow cytometry analysis of the healthy human immune system [1]. These data are available to researchers and have value as a reference range for research involving peripheral cytokines.

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References

Yi J, Rosa-Bray M, Staats J, Zakroysky P, Chan C, Russo M . Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling. PLoS One. 2019; 14(12):e0225512. PMC: 6905525. DOI: 10.1371/journal.pone.0225512. View

Li Y, Yi J, Russo M, Rosa-Bray M, Weinhold K, Guptill J . Normative dataset for plasma cytokines in healthy human adults. Data Brief. 2021; 35:106857. PMC: 7900339. DOI: 10.1016/j.dib.2021.106857. View