Relax, Keep Walking - A Practical Guide to Continuous Phylogeographic Inference with BEAST

Overview

Journal Mol Biol Evol

Publisher Oxford University Press

Specialty Biology

Date 2021 Feb 2

PMID 33528560

Citations 26

Authors

Simon Dellicour

Mandev S Gill

Nuno R Faria

Andrew Rambaut

Oliver G Pybus

Marc A Suchard

Philippe Lemey

Affiliations

Soon will be listed here.

Abstract

Spatially explicit phylogeographic analyses can be performed with an inference framework that employs relaxed random walks to reconstruct phylogenetic dispersal histories in continuous space. This core model was first implemented 10 years ago and has opened up new opportunities in the field of phylodynamics, allowing researchers to map and analyze the spatial dissemination of rapidly evolving pathogens. We here provide a detailed and step-by-step guide on how to set up, run, and interpret continuous phylogeographic analyses using the programs BEAUti, BEAST, Tracer, and TreeAnnotator.

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