Visualization of Microwave Near-field Distribution in Sodium Chloride and Glucose Aqueous Solutions by a Thermo-elastic Optical Indicator Microscope

Overview

Journal Sci Rep

Specialty Science

Date 2021 Jan 29

PMID 33510224

Citations 2

Authors

Zhirayr Baghdasaryan

Arsen Babajanyan

Levon Odabashyan

Jung-Ha Lee

Barry Friedman

Kiejin Lee

Affiliations

Soon will be listed here.

Abstract

In this study, a new optical method is presented to determine the concentrations of NaCl and glucose aqueous solutions by using a thermo-elastic optical indicator microscope. By measuring the microwave near-field distribution intensity, concentration changes of NaCl and glucose aqueous solutions were detected in the 0-100 mg/ml range, when exposed to microwave irradiation at 12 GHz frequency. Microwave near-field distribution intensity decreased as the NaCl or glucose concentration increased due to the changes of the absorption properties of aqueous solution. This method provides a novel approach for monitoring NaCl and glucose in biological liquids by using a CCD sensor capable of visualizing NaCl and glucose concentrations without scanning.

Citing Articles

Dielectric characterization and modelling of aqueous solutions involving sodium chloride and sucrose and application to the design of a bi-parameter RF-sensor.

Bakam Nguenouho O, Chevalier A, Potelon B, Benedicto J, Quendo C Sci Rep. 2022; 12(1):7209.

PMID: 35505075 PMC: 9065094. DOI: 10.1038/s41598-022-11355-w.

3D visualization of microwave electric and magnetic fields by using a metasurface-based indicator.

Baghdasaryan Z, Babajanyan A, Parsamyan H, Friedman B, Kim S, Lee J Sci Rep. 2022; 12(1):6150.

PMID: 35414676 PMC: 9005508. DOI: 10.1038/s41598-022-10073-7.

References

Romanzetti S, Mirkes C, Fiege D, Celik A, Felder J, Jon Shah N . Mapping tissue sodium concentration in the human brain: a comparison of MR sequences at 9.4Tesla. Neuroimage. 2014; 96:44-53. DOI: 10.1016/j.neuroimage.2014.03.079. View

Han S . Anionic effects on the structure and dynamics of water in superconcentrated aqueous electrolytes. RSC Adv. 2022; 9(2):609-619. PMC: 9059539. DOI: 10.1039/c8ra09589b. View

Zhong C, Deng Y, Hu W, Qiao J, Zhang L, Zhang J . A review of electrolyte materials and compositions for electrochemical supercapacitors. Chem Soc Rev. 2015; 44(21):7484-539. DOI: 10.1039/c5cs00303b. View

Gabriel E, Garcia P, Cardoso T, Lopes F, Martins F, Coltro W . Highly sensitive colorimetric detection of glucose and uric acid in biological fluids using chitosan-modified paper microfluidic devices. Analyst. 2016; 141(15):4749-56. DOI: 10.1039/c6an00430j. View

Sajib S, Lee M, Kim H, Woo E, Kwon O . Extracellular Total Electrolyte Concentration Imaging for Electrical Brain Stimulation (EBS). Sci Rep. 2018; 8(1):290. PMC: 5762666. DOI: 10.1038/s41598-017-18515-3. View

Awad S, Allison S, Lobo D . The history of 0.9% saline. Clin Nutr. 2008; 27(2):179-88. DOI: 10.1016/j.clnu.2008.01.008. View

Madelin G, Regatte R . Biomedical applications of sodium MRI in vivo. J Magn Reson Imaging. 2013; 38(3):511-29. PMC: 3759542. DOI: 10.1002/jmri.24168. View

Yoshikawa N . Fundamentals and applications of microwave heating of metals. J Microw Power Electromagn Energy. 2011; 44(1):4-13. DOI: 10.1080/08327823.2010.11689772. View

Feng J, Huang P, Wu F . Gold-platinum bimetallic nanoclusters with enhanced peroxidase-like activity and their integrated agarose hydrogel-based sensing platform for the colorimetric analysis of glucose levels in serum. Analyst. 2017; 142(21):4106-4115. DOI: 10.1039/c7an01343d. View

10.

Timko J, Bucher D, Kuyucak S . Dissociation of NaCl in water from ab initio molecular dynamics simulations. J Chem Phys. 2010; 132(11):114510. DOI: 10.1063/1.3360310. View

11.

Kim J, Babajanyan A, Hovsepyan A, Lee K, Friedman B . Microwave dielectric resonator biosensor for aqueous glucose solution. Rev Sci Instrum. 2008; 79(8):086107. DOI: 10.1063/1.2968115. View

12.

Dautta M, Alshetaiwi M, Escobar J, Tseng P . Passive and wireless, implantable glucose sensing with phenylboronic acid hydrogel-interlayer RF resonators. Biosens Bioelectron. 2020; 151:112004. PMC: 7043278. DOI: 10.1016/j.bios.2020.112004. View

13.

Liu Y, Wang H, Zhao W, Zhang M, Qin H, Xie Y . Flexible, Stretchable Sensors for Wearable Health Monitoring: Sensing Mechanisms, Materials, Fabrication Strategies and Features. Sensors (Basel). 2018; 18(2). PMC: 5856015. DOI: 10.3390/s18020645. View

14.

Mohd Bahar A, Zakaria Z, Md Arshad M, Isa A, Dasril Y, Alahnomi R . Real Time Microwave Biochemical Sensor Based on Circular SIW Approach for Aqueous Dielectric Detection. Sci Rep. 2019; 9(1):5467. PMC: 6445140. DOI: 10.1038/s41598-019-41702-3. View

15.

Kim N, Adhikari K, Dhakal R, Chuluunbaatar Z, Wang C, Kim E . Rapid, sensitive, and reusable detection of glucose by a robust radiofrequency integrated passive device biosensor chip. Sci Rep. 2015; 5:7807. PMC: 4295091. DOI: 10.1038/srep07807. View

16.

Narang R, Mohammadi S, Ashani M, Sadabadi H, Hejazi H, Zarifi M . Sensitive, Real-time and Non-Intrusive Detection of Concentration and Growth of Pathogenic Bacteria using Microfluidic-Microwave Ring Resonator Biosensor. Sci Rep. 2018; 8(1):15807. PMC: 6202403. DOI: 10.1038/s41598-018-34001-w. View

17.

Eldamak A, Thorson S, Fear E . Study of the Dielectric Properties of Artificial Sweat Mixtures at Microwave Frequencies. Biosensors (Basel). 2020; 10(6). PMC: 7344616. DOI: 10.3390/bios10060062. View

18.

Baghelani M, Abbasi Z, Daneshmand M, Light P . Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators. Sci Rep. 2020; 10(1):12980. PMC: 7395170. DOI: 10.1038/s41598-020-69547-1. View

19.

Zhao L, Ma K, Yang Z . Changes of water hydrogen bond network with different externalities. Int J Mol Sci. 2015; 16(4):8454-89. PMC: 4425091. DOI: 10.3390/ijms16048454. View

20.

Juan C, Bronchalo E, Potelon B, Quendo C, Sabater-Navarro J . Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors. Sensors (Basel). 2019; 19(17). PMC: 6749577. DOI: 10.3390/s19173779. View