» Articles » PMID: 33505937

Comparison of Phytochemical Contents and Cytoprotective Effects of Different Rice Bran Extracts from and Rice Cultivars

Overview
Date 2021 Jan 28
PMID 33505937
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

The present study was aimed to evaluate the phytochemical contents and hepatocyte protective effects of functional extracts from rice bran of and rice cultivars, Dasan 1 and Ilpum, respectively. The highest vitamin E (23.51 mg/g) and phytosterol (390.25 mg/g) content was observed in the unsaponifiable matter (USM) of Dasan 1 cultivar. However, USM of Ilpum showed the highest content of total policosanol and squalene (232.73 mg/g and 99.31 mg/g, respectively). The methanolic extract from the defatted rice bran (MEDR) of Dasan 1 showed the highest total polyphenol content, reducing power, and radical scavenging capacity, while USM of Dasan 1 showed the highest cell viability (81.3%) against oxidative stress in HepG2 cells. USM significantly increased glutathione levels and suppressed the production of reactive oxygen species in hepatocytes compared with methanolic extracts of the rice bran oils and/or MEDR. These results provide useful information on the functional extracts of rice bran from and rice cultivars, including their antioxidant properties and cytoprotection in HepG2 cells.

Citing Articles

Hypoglycemic and hypolipidemic effects of unsaponifiable matter from okra seed in diabetic rats.

Seo D, Kim N, Jeon A, Kwon J, Baek I, Shin E Nutr Res Pract. 2024; 18(3):345-356.

PMID: 38854468 PMC: 11156772. DOI: 10.4162/nrp.2024.18.3.345.


Consumption of Policosanol (Raydel) Improves Hepatic, Renal, and Reproductive Functions in Zebrafish: In Vivo Comparison Study among Cuban, Chinese, and American Policosanol.

Cho K, Kim J, Nam H, Baek S, Bahuguna A Pharmaceuticals (Basel). 2024; 17(1).

PMID: 38256899 PMC: 10818973. DOI: 10.3390/ph17010066.


Unsaponifiable Matter from Wheat Bran Cultivated in Korea Inhibits Hepatic Lipogenesis by Activating AMPK Pathway.

An M, Heo H, Park J, Jeong H, Kim Y, Lee J Foods. 2023; 12(21).

PMID: 37959135 PMC: 10650137. DOI: 10.3390/foods12214016.

References
1.
Termini J . Hydroperoxide-induced DNA damage and mutations. Mutat Res. 2000; 450(1-2):107-24. DOI: 10.1016/s0027-5107(00)00019-1. View

2.
Myhrstad M, Carlsen H, Nordstrom O, Blomhoff R, Moskaug J . Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter. Free Radic Biol Med. 2002; 32(5):386-93. DOI: 10.1016/s0891-5849(01)00812-7. View

3.
Pellegrini N, Simonetti P, Gardana C, Brenna O, Brighenti F, Pietta P . Polyphenol content and total antioxidant activity of vini novelli (young red wines). J Agric Food Chem. 2000; 48(3):732-5. DOI: 10.1021/jf990251v. View

4.
Xu D, Li Y, Meng X, Zhou T, Zhou Y, Zheng J . Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources. Int J Mol Sci. 2017; 18(1). PMC: 5297730. DOI: 10.3390/ijms18010096. View

5.
Cho E, Lee K, Lee H . Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK. Mutat Res. 2008; 640(1-2):123-30. DOI: 10.1016/j.mrfmmm.2007.12.012. View