Voltammetric Determination of Itopride Using Carbon Paste Electrode Modified with Gd Doped TiO2 Nanotubes

Overview

Journal Turk J Chem

Publisher Scientific and Technological Research Council of Turkey

Date 2021 Jan 25

PMID 33488217

Citations 1

Authors

Abdulaziz Nabil Amro

Khadijah Emran

Hessah Alanazi

Affiliations

Soon will be listed here.

Abstract

In the present work TiO nanotubes (TNT) have been synthesized by alkaline hydrothermal transformation. Then they have been doped with Gd element. Characterizations of doped and undoped TNT have been done with TEM and SEM. The chemical composition was analyzed by EDX, Raman and FTIR spectroscopy. The crystal structure was characterized by XRD. Carbon paste electrode has been fabricated and mixed with Gd doped and undoped TNT to form a nanocomposite working electrode. Comparison of bare carbon paste electrode and Gd doped and undoped TNT carbon paste electrode for 1.0 ×10 M K [Fe(CN)] voltammetric analysis; it was observed that Gd doped TNT modified electrode has advantage of high sensitivity. Gd doped TNT modified electrode has been used as working electrode for itopride assay in a pharmaceutical formulation. Cyclic voltammetry analysis showed high correlation coefficient of 0.9973 for itopride (0.04-0.2 mg/mL) with a limit of detection (LOD) and limit of quantitation values (LOQ) of 2.9 and 23.0 μg.mL respectively.

Citing Articles

Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode.

Ozturk F, Yuksel E, Erden P, Kilic E Turk J Chem. 2023; 47(1):126-136.

PMID: 37720854 PMC: 10504013. DOI: 10.55730/1300-0527.3523.

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