Detection of Trypanosoma Cruzi in the Saliva of Diverse Neotropical Bats

Overview

Journal Zoonoses Public Health

Specialties Public Health
Veterinary Medicine

Date 2021 Jan 23

PMID 33484236

Citations 8

Authors

Laura M Bergner

Daniel J Becker

Carlos Tello

Jorge E Carrera

Daniel G Streicker

Affiliations

Soon will be listed here.

Abstract

Trypanosoma cruzi is widely reported in bats, yet transmission routes remain unclear. We present evidence from metagenomic sequence data that T. cruzi occurs in the saliva of diverse Neotropical bats. Phylogenetic analyses demonstrated that the bat-associated T. cruzi sequences described here formed part of a bat-specific clade, suggesting an independent transmission cycle. Our results highlight the value in repurposing metagenomic data generated for viral discovery to reveal insights into the biology of other parasites. Evaluating whether the presence of T. cruzi in the saliva of two hematophagous bat species represents an ecological route for zoonotic transmission of Chagas disease is an interesting avenue for future research.

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