Experimental Protocols for MRI Mapping of Renal T

Overview

Journal Methods Mol Biol

Specialty Molecular Biology

Date 2021 Jan 21

PMID 33476012

Citations 1

Authors

Philippe Garteiser

Octavia Bane

Sabrina Doblas

Iris Friedli

Stefanie Hectors

Gwenael Page

Bernard E Van Beers

John C Waterton

Affiliations

Soon will be listed here.

Abstract

The water proton longitudinal relaxation time, T, is a common and useful MR parameter in nephrology research. Here we provide three step-by-step T-mapping protocols suitable for different types of nephrology research. Firstly, we provide a single-slice 2D saturation recovery protocol suitable for studies of global pathology, where whole-kidney coverage is unnecessary. Secondly, we provide an inversion recovery type imaging protocol that may be optimized for specific kidney disease applications. Finally, we also provide imaging protocol for small animal kidney imaging in a clinical scanner.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This analysis protocol chapter is complemented by two separate chapters describing the basic concept and experimental procedure.

Citing Articles

Optimization of Fair Arterial Spin Labeling Magnetic Resonance Imaging (ASL-MRI) for Renal Perfusion Quantification in Dogs: Pilot Study.

Hillaert A, Sanmiguel Serpa L, Xu Y, Hesta M, Bogaert S, Vanderperren K Animals (Basel). 2024; 14(12).

PMID: 38929429 PMC: 11201026. DOI: 10.3390/ani14121810.

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