» Articles » PMID: 33473722

Complete Mitochondrial Genome of an Extinct Specimen from Denisova Cave (Altai, Russia)

Overview
Date 2021 Jan 21
PMID 33473722
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

is an extinct subgenus of first characterized and delineated in 2010. The almost complete mitochondrial genome is available only for a single specimen of - a 40,000 years old from Proskuryakova cave (Khakassia, Russia). Our studies of ancient horses from Denisova cave (Altai, Russia) revealed mitochondrial DNA of this species in a 32,000 years old sample. Using alignments to multiple mitochondrial genomes of non-caballine equids, we recovered 100% complete mitochondrial genome of for the first time. Phylogenetic analysis demonstrates close relationship between this individual and the one previously described in Khakassia.

Citing Articles

Radiocarbon and genomic evidence for the survival of until the late Holocene.

Cai D, Zhu S, Gong M, Zhang N, Wen J, Liang Q Elife. 2022; 11.

PMID: 35543411 PMC: 9142152. DOI: 10.7554/eLife.73346.


Molecular identification of late and terminal Pleistocene Equus ovodovi from northeastern China.

Yuan J, Hou X, Barlow A, Preick M, Taron U, Alberti F PLoS One. 2019; 14(5):e0216883.

PMID: 31095634 PMC: 6522033. DOI: 10.1371/journal.pone.0216883.

References
1.
Vilstrup J, Seguin-Orlando A, Stiller M, Ginolhac A, Raghavan M, Nielsen S . Mitochondrial phylogenomics of modern and ancient equids. PLoS One. 2013; 8(2):e55950. PMC: 3577844. DOI: 10.1371/journal.pone.0055950. View

2.
Maricic T, Whitten M, Paabo S . Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS One. 2010; 5(11):e14004. PMC: 2982832. DOI: 10.1371/journal.pone.0014004. View

3.
Orlando L, Metcalf J, Alberdi M, Telles-Antunes M, Bonjean D, Otte M . Revising the recent evolutionary history of equids using ancient DNA. Proc Natl Acad Sci U S A. 2009; 106(51):21754-9. PMC: 2799835. DOI: 10.1073/pnas.0903672106. View

4.
Orlando L . A 400,000-year-old mitochondrial genome questions phylogenetic relationships amongst archaic hominins: using the latest advances in ancient genomics, the mitochondrial genome sequence of a 400,000-year-old hominin has been deciphered. Bioessays. 2014; 36(6):598-605. DOI: 10.1002/bies.201400018. View

5.
Druzhkova A, Thalmann O, Trifonov V, Leonard J, Vorobieva N, Ovodov N . Ancient DNA analysis affirms the canid from Altai as a primitive dog. PLoS One. 2013; 8(3):e57754. PMC: 3590291. DOI: 10.1371/journal.pone.0057754. View