Trends and Risk Factors of Lung Cancer in China

Overview

Journal Chin J Cancer Res

Specialty Oncology

Date 2021 Jan 15

PMID 33446992

Citations 21

Authors

Siyi He

He Li

Maomao Cao

Dianqin Sun

Lin Lei

Ni Li

Ji Peng

Wanqing Chen

Affiliations

Soon will be listed here.

Abstract

China is faced with heavy burdens caused by lung cancer, which has climbed to the top of both cancer incidence and mortality spectrums. The age-standardized rates of incidence and mortality have shown a trend of gradual up-trends in the last decades, while the crude rates rise much quickly due to the aging of population. Although the improvement in health care has contributed to better survival of lung cancer, its prognosis is still challenging. Apart from the common risk factors such as tobacco use, air pollution, and occupational hazards, some specific factors like Chinese-style cooking also have posed great threats to human health. In light of such national conditions, specific interventions should be conducted to curb the burden of lung cancer including smoking cessation, improvement of air quality, early detection and effective treatment of lung cancer.

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References

Aberle D, Adams A, Berg C, Black W, Clapp J, Fagerstrom R . Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365(5):395-409. PMC: 4356534. DOI: 10.1056/NEJMoa1102873. View

Zou X, Lin D, Wan X, Chao A, Feng Q, Dai Z . Histological subtypes of lung cancer in Chinese males from 2000 to 2012. Biomed Environ Sci. 2014; 27(1):3-9. DOI: 10.3967/bes2014.010. View

Zhang S, Zheng R, Yang Z, Zeng H, Sun K, Gu X . [Trend analysis on incidence and age at diagnosis for lung cancer in cancer registration areas of China, 2000-2014]. Zhonghua Yu Fang Yi Xue Za Zhi. 2018; 52(6):579-585. DOI: 10.3760/cma.j.issn.0253-9624.2018.06.005. View

Gordon S, Bruce N, Grigg J, Hibberd P, Kurmi O, Hubert Lam K . Respiratory risks from household air pollution in low and middle income countries. Lancet Respir Med. 2014; 2(10):823-60. PMC: 5068561. DOI: 10.1016/S2213-2600(14)70168-7. View

Liu S, Chen Q, Guo L, Cao X, Sun X, Chen W . Incidence and mortality of lung cancer in China, 20082012. Chin J Cancer Res. 2019; 30(6):580-587. PMC: 6328502. DOI: 10.21147/j.issn.1000-9604.2018.06.02. View

Xu D, Shang B, Cao Z . [Investigation of key indoor air pollutants in residence in part of the cities in China]. Wei Sheng Yan Jiu. 2007; 36(4):473-6. View

Islami F, Chen W, Yu X, Lortet-Tieulent J, Zheng R, Flanders W . Cancer deaths and cases attributable to lifestyle factors and infections in China, 2013. Ann Oncol. 2017; 28(10):2567-2574. DOI: 10.1093/annonc/mdx342. View

. Household use of solid fuels and high-temperature frying. IARC Monogr Eval Carcinog Risks Hum. 2010; 95:1-430. PMC: 5046077. View

Adami H, Bergstrom R, Holmberg L, Klareskog L, Persson I, Ponten J . The effect of female sex hormones on cancer survival. A register-based study in patients younger than 20 years at diagnosis. JAMA. 1990; 263(16):2189-93. View

10.

Nasim F, Sabath B, Eapen G . Lung Cancer. Med Clin North Am. 2019; 103(3):463-473. DOI: 10.1016/j.mcna.2018.12.006. View

11.

Guo X, Fu Z, Sun J, Lu Z, Zhang J, Chu J . [Trend of mortality and decomposition on malignant tumors in Shandong province, 1970-2013]. Zhonghua Liu Xing Bing Xue Za Zhi. 2019; 40(8):924-929. DOI: 10.3760/cma.j.issn.0254-6450.2019.08.010. View

12.

Li F, Huang L, Hu C, Gu Q, Zhu X . [Comparative analysis of clinical epidemiology and pathological characteristics of 908 patients with primary lung cancer of Hunan Province in 1997 and 2007]. Zhongguo Fei Ai Za Zhi. 2010; 13(4):326-30. PMC: 6000424. DOI: 10.3779/j.issn.1009-3419.2010.04.11. View

13.

Zhang D, Qian X, Chu S, Jing H, Tong Z, Liang L . [Level and trend of respiratory diseases mortality in China from 2002 to 2016]. Zhonghua Yi Xue Za Zhi. 2020; 100(24):1895-1900. DOI: 10.3760/cma.j.cn112137-20191108-02430. View

14.

Cen X, Wang D, Sun W, Cao L, Zhang Z, Wang B . The trends of mortality and years of life lost of cancers in urban and rural areas in China, 1990-2017. Cancer Med. 2019; 9(4):1562-1571. PMC: 7013076. DOI: 10.1002/cam4.2765. View

15.

Han L, Zhou W, Pickett S, Li W, Qian Y . Multicontaminant air pollution in Chinese cities. Bull World Health Organ. 2018; 96(4):233-242E. PMC: 5872009. DOI: 10.2471/BLT.17.195560. View

16.

Guo Y, Zeng H, Zheng R, Li S, Barnett A, Zhang S . The association between lung cancer incidence and ambient air pollution in China: A spatiotemporal analysis. Environ Res. 2015; 144(Pt A):60-65. DOI: 10.1016/j.envres.2015.11.004. View

17.

Wang M, Luo X, Xu S, Liu W, Ding F, Zhang X . Trends in smoking prevalence and implication for chronic diseases in China: serial national cross-sectional surveys from 2003 to 2013. Lancet Respir Med. 2018; 7(1):35-45. DOI: 10.1016/S2213-2600(18)30432-6. View

18.

Francisci S, Minicozzi P, Pierannunzio D, Ardanaz E, Eberle A, Grimsrud T . Survival patterns in lung and pleural cancer in Europe 1999-2007: Results from the EUROCARE-5 study. Eur J Cancer. 2015; 51(15):2242-2253. DOI: 10.1016/j.ejca.2015.07.033. View

19.

Nesbitt J, Putnam Jr J, Walsh G, Roth J, Mountain C . Survival in early-stage non-small cell lung cancer. Ann Thorac Surg. 1995; 60(2):466-72. DOI: 10.1016/0003-4975(95)00169-l. View

20.

Wang L, Liu C, Meng X, Niu Y, Lin Z, Liu Y . Associations between short-term exposure to ambient sulfur dioxide and increased cause-specific mortality in 272 Chinese cities. Environ Int. 2018; 117:33-39. DOI: 10.1016/j.envint.2018.04.019. View