» Articles » PMID: 33420086

Nurture Might Be Nature: Cautionary Tales and Proposed Solutions

Overview
Journal NPJ Sci Learn
Specialty Psychology
Date 2021 Jan 9
PMID 33420086
Citations 47
Authors
Affiliations
Soon will be listed here.
Abstract

Across a wide range of studies, researchers often conclude that the home environment and children's outcomes are causally linked. In contrast, behavioral genetic studies show that parents influence their children by providing them with both environment and genes, meaning the environment that parents provide should not be considered in the absence of genetic influences, because that can lead to erroneous conclusions on causation. This article seeks to provide behavioral scientists with a synopsis of numerous methods to estimate the direct effect of the environment, controlling for the potential of genetic confounding. Ideally, using genetically sensitive designs can fully disentangle this genetic confound, but these require specialized samples. In the near future, researchers will likely have access to measured DNA variants (summarized in a polygenic scores), which could serve as a partial genetic control, but that is currently not an option that is ideal or widely available. We also propose a work around for when genetically sensitive data are not readily available: the Familial Control Method. In this method, one measures the same trait in the parents as the child, and the parents' trait is then used as a covariate (e.g., a genetic proxy). When these options are all not possible, we plead with our colleagues to clearly mention genetic confound as a limitation, and to be cautious with any environmental causal statements which could lead to unnecessary parent blaming.

Citing Articles

Language aptitude is related to the anatomy of the transverse temporal gyri.

Ramoser C, Fischer A, Caspers J, Schiller N, Golestani N, Kepinska O Brain Struct Funct. 2024; 230(1):14.

PMID: 39702671 PMC: 11659347. DOI: 10.1007/s00429-024-02883-4.


Interaction of family SES with children's genetic propensity for cognitive and noncognitive skills: No evidence of the Scarr-Rowe hypothesis for educational outcomes.

Ghirardi G, Gil-Hernandez C, Bernardi F, van Bergen E, Demange P Res Soc Stratif Mobil. 2024; 92:100960.

PMID: 39220821 PMC: 11364161. DOI: 10.1016/j.rssm.2024.100960.


Exposure to Language in Video and its Impact on Linguistic Development in Children Aged 3-11: A Scoping Review.

Gowenlock A, Norbury C, Rodd J J Cogn. 2024; 7(1):57.

PMID: 39035076 PMC: 11259113. DOI: 10.5334/joc.385.


Longitudinal trajectories of brain development from infancy to school age and their relationship to literacy development.

Turesky T, Escalante E, Loh M, Gaab N bioRxiv. 2024; .

PMID: 39005343 PMC: 11244924. DOI: 10.1101/2024.06.29.601366.


Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization.

Patrizia P, Pingault J, Eley T, McCrory E, Viding E Res Sq. 2024; .

PMID: 38883746 PMC: 11177992. DOI: 10.21203/rs.3.rs-4409798/v1.


References
1.
McAdams T, Neiderhiser J, Rijsdijk F, Narusyte J, Lichtenstein P, Eley T . Accounting for genetic and environmental confounds in associations between parent and child characteristics: a systematic review of children-of-twins studies. Psychol Bull. 2014; 140(4):1138-73. DOI: 10.1037/a0036416. View

2.
de Zeeuw E, Hottenga J, Ouwens K, Dolan C, Ehli E, Davies G . Intergenerational Transmission of Education and ADHD: Effects of Parental Genotypes. Behav Genet. 2020; 50(4):221-232. PMC: 7355279. DOI: 10.1007/s10519-020-09992-w. View

3.
Lemery-Chalfant K, Kao K, Swann G, Goldsmith H . Childhood temperament: passive gene-environment correlation, gene-environment interaction, and the hidden importance of the family environment. Dev Psychopathol. 2013; 25(1):51-63. PMC: 3581153. DOI: 10.1017/S0954579412000892. View

4.
Selzam S, Dale P, Wagner R, DeFries J, Cederlof M, OReilly P . Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years. Sci Stud Read. 2017; 21(4):334-349. PMC: 5490720. DOI: 10.1080/10888438.2017.1299152. View

5.
Petersen A, Lange T . What Is the Causal Interpretation of Sibling Comparison Designs?. Epidemiology. 2019; 31(1):75-81. DOI: 10.1097/EDE.0000000000001108. View