Erectile Dysfunction Treatment Using Stem Cells: A Review
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Erectile dysfunction (ED) is a disorder that affects the quality of life and the sexual relations of more than half of the male population aged over 40 years. The prediction regarding the incidence of ED is devastating as it is expected that this disorder will affect more than 300 million men in the next five years. Several studies have suggested the use of stem cells for the treatment of ED and showed that this type of treatment is promising in terms of damaged tissue repair as well as of clinical efficacy; however, there are several gaps in the knowledge and evidence is lacking. In order to highlight a few of them in this review, we performed a research of the literature focusing on currently available clinical studies regarding the clinical efficacy of stem cell administration for the treatment of ED. We reviewed the methods of administration, the cell types used in the performed clinical trials and the safety and efficiency of such procedures. We conclude that there are rapidly expanding and promising results from the reported clinical studies indicating that stem cells could indeed be a potential treatment for patients with ED although more studies are necessary.
Hammad M, Miller J, Sultan M, Abou Chawareb E, Nakamura H, Martinez J Ther Adv Urol. 2025; 17:17562872251322651.
PMID: 39996014 PMC: 11848873. DOI: 10.1177/17562872251322651.
Sonawane T, Kashte S, Khera S, Bahulkar A, Cuddapah C, Kadam S J Assist Reprod Genet. 2024; 41(8):2037-2051.
PMID: 39023828 PMC: 11339218. DOI: 10.1007/s10815-024-03165-y.
Digholkar G, Varghese R, Pal K, Sharma R Int J Impot Res. 2024; 36(8):818-819.
PMID: 38443556 DOI: 10.1038/s41443-024-00866-x.
Application of Stem Cell in Human Erectile Dysfunction - A Systematic Review.
Siregar S, Novesar A, Mustafa A Res Rep Urol. 2022; 14:379-388.
PMID: 36320568 PMC: 9618244. DOI: 10.2147/RRU.S376556.
Wani M, Rai B, Webb W, Madaan S Ther Adv Urol. 2022; 14:17562872221086999.
PMID: 35371295 PMC: 8972940. DOI: 10.1177/17562872221086999.