Bioprinting for the Biologist

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2021 Jan 8

PMID 33417859

Citations 102

Authors

Andrew C Daly

Margaret E Prendergast

Alex J Hughes

Jason A Burdick

Affiliations

Soon will be listed here.

Abstract

Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportunities for bioprinting within biology, such as for exploring cellular crosstalk or cellular morphogenesis. The overall goals of this Primer are to provide an overview of bioprinting with the biologist in mind, outline the steps in extrusion bioprinting (the most widely used and accessible technology), and discuss alternative bioprinting technologies and future opportunities for bioprinting in biology.

Citing Articles

Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction.

Jia L, Liu S, Gu L, Liu X, Sun K, Chu F Bioact Mater. 2025; 48:100-117.

PMID: 40034808 PMC: 11874231. DOI: 10.1016/j.bioactmat.2025.02.011.

Numerical modeling of oxygen diffusion in tissue spheroids undergoing fusion using function representation and finite volumes.

Vilinski-Mazur K, Kirillov B, Rogozin O, Kolomenskiy D Sci Rep. 2025; 15(1):5054.

PMID: 39934150 PMC: 11814134. DOI: 10.1038/s41598-025-86805-2.

DNA-encoded dynamic hydrogels for 3D bioprinted cartilage organoids.

Chen Z, Zhang H, Huang J, Weng W, Geng Z, Li M Mater Today Bio. 2025; 31:101509.

PMID: 39925718 PMC: 11803226. DOI: 10.1016/j.mtbio.2025.101509.

3D-Printed Myocardium-Specific Structure Enhances Maturation and Therapeutic Efficacy of Engineered Heart Tissue in Myocardial Infarction.

Wu Y, Wang Y, Xiao M, Zhang G, Zhang F, Tang M Adv Sci (Weinh). 2025; 12(10):e2409871.

PMID: 39840547 PMC: 11905000. DOI: 10.1002/advs.202409871.

Sacrificial capillary pumps to engineer multiscalar biological forms.

Sundaram S, Lee J, Bjorge I, Michas C, Kim S, Lammers A Nature. 2024; 636(8042):361-367.

PMID: 39663490 DOI: 10.1038/s41586-024-08175-5.

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