Sociodemographic and Clinical Characteristics of Geriatric Patients with Psoriasis Receiving Narrowband Ultraviolet B Phototherapy

Overview

Journal Ann Geriatr Med Res

Specialty Geriatrics

Date 2021 Jan 4

PMID 33389975

Citations 1

Authors

Lili Legiawati

Rinadewi Astriningrum

Shannaz Nadia Yusharyahya

Vivianne Chandrakesuma

Affiliations

Soon will be listed here.

Abstract

Background: Although the demographic and clinical characteristics of patients with psoriasis have been evaluated in many countries, studies specifically on geriatric patients remain scarce and none have focused on those receiving phototherapy. This study describes the sociodemographic and clinical characteristics of geriatric patients with psoriasis in Indonesia, specifically those who received narrowband ultraviolet B (NB-UVB) phototherapy.

Methods: This retrospective study using data obtained from phototherapy and medical records of psoriasis patients who received phototherapy in 2014-2019 was conducted at the Dermatovenereology Clinic of Dr. Cipto Mangunkusumo National General Hospital.

Results: Among 24 geriatric patients with psoriasis who received NB-UVB phototherapy, the median age of onset was 61 years (range, 36-74 years). Regarding comorbidities, 15 patients (62.5%) had dyslipidemia, 15 patients (62.5%) had hypertension, 11 patients (45.8%) had obesity, 9 patients (37.5%) had periodontitis/gingivitis, 9 patients (37.5%) had type 2 diabetes mellitus, and 6 patients (25.0%) had hyperuricemia.

Conclusion: Some comorbidities have been associated with psoriasis, including metabolic syndrome and periodontitis. The data from this study could help physicians in evaluating and making appropriate clinical decisions when managing psoriasis patients in the geriatric population.

Citing Articles

Skin Disease Profile in Geriatric Inpatients at a Tertiary Referral Hospital.

Legiawati L, Yusharyahya S, Astriningrum R, Pulungan A, Kusumahapsari R Malays J Med Sci. 2024; 30(6):54-60.

PMID: 38239249 PMC: 10793136. DOI: 10.21315/mjms2023.30.6.6.

References

Mallbris L, Granath F, Hamsten A, Stahle M . Psoriasis is associated with lipid abnormalities at the onset of skin disease. J Am Acad Dermatol. 2006; 54(4):614-21. DOI: 10.1016/j.jaad.2005.11.1079. View

Kostovic K, Zuzul K, Ceovic R, Bukvic Mokos Z . Psoriasis in the mature patient: Therapeutic approach in the era of biologics. Clin Dermatol. 2018; 36(2):222-230. DOI: 10.1016/j.clindermatol.2017.10.013. View

Lee J, Kang S, Park J, Jo S . Prevalence of Psoriasis in Korea: A Population-Based Epidemiological Study Using the Korean National Health Insurance Database. Ann Dermatol. 2017; 29(6):761-767. PMC: 5705359. DOI: 10.5021/ad.2017.29.6.761. View

Keller J, Lin H . The effects of chronic periodontitis and its treatment on the subsequent risk of psoriasis. Br J Dermatol. 2012; 167(6):1338-44. DOI: 10.1111/j.1365-2133.2012.11126.x. View

Parisi R, Symmons D, Griffiths C, Ashcroft D . Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2012; 133(2):377-85. DOI: 10.1038/jid.2012.339. View

Kassi K, Djeha D, Gbery I, Kouame K, Sangare A . Psoriasis in elderly patients in the Côte d'Ivoire: socio-demographic, clinical, and therapeutic aspects, and follow-up. Int J Dermatol. 2015; 55(2):e83-6. DOI: 10.1111/ijd.13138. View

Takeshita J, Grewal S, Langan S, Mehta N, Ogdie A, Van Voorhees A . Psoriasis and comorbid diseases: Implications for management. J Am Acad Dermatol. 2017; 76(3):393-403. PMC: 5839668. DOI: 10.1016/j.jaad.2016.07.065. View

Wu S, Han J, Li W, Qureshi A . Hypertension, antihypertensive medication use, and risk of psoriasis. JAMA Dermatol. 2014; 150(9):957-63. PMC: 4184206. DOI: 10.1001/jamadermatol.2013.9957. View

Chen K, Wang G, Jin H, Xu J, Zhu X, Zheng M . Clinic characteristics of psoriasis in China: a nationwide survey in over 12000 patients. Oncotarget. 2017; 8(28):46381-46389. PMC: 5542274. DOI: 10.18632/oncotarget.18453. View

10.

Shah K, Mellars L, Changolkar A, Feldman S . Real-world burden of comorbidities in US patients with psoriasis. J Am Acad Dermatol. 2017; 77(2):287-292.e4. DOI: 10.1016/j.jaad.2017.03.037. View

11.

Yosipovitch G, Tang M . Practical management of psoriasis in the elderly: epidemiology, clinical aspects, quality of life, patient education and treatment options. Drugs Aging. 2002; 19(11):847-63. DOI: 10.2165/00002512-200219110-00003. View

12.

Moutsopoulos N, Kling H, Angelov N, Jin W, Palmer R, Nares S . Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis. J Autoimmun. 2012; 39(4):294-303. PMC: 3416947. DOI: 10.1016/j.jaut.2012.03.003. View

13.

Strober B, Karki C, Mason M, Guo N, Holmgren S, Greenberg J . Characterization of disease burden, comorbidities, and treatment use in a large, US-based cohort: Results from the Corrona Psoriasis Registry. J Am Acad Dermatol. 2017; 78(2):323-332. DOI: 10.1016/j.jaad.2017.10.012. View

14.

Cohen A, KAGEN M, Friger M, Halevy S . Calcium channel blockers intake and psoriasis: a case-control study. Acta Derm Venereol. 2002; 81(5):347-9. DOI: 10.1080/000155501317140061. View

15.

Su N, Huang J, Hu C, Yu H, Chang Y . Increased risk of periodontitis in patients with psoriatic disease: a nationwide population-based retrospective cohort study. PeerJ. 2017; 5:e4064. PMC: 5694656. DOI: 10.7717/peerj.4064. View

16.

Kwon H, Kwon I, Youn J . Clinical study of psoriasis occurring over the age of 60 years: is elderly-onset psoriasis a distinct subtype?. Int J Dermatol. 2011; 51(1):53-8. DOI: 10.1111/j.1365-4632.2011.04979.x. View

17.

Affandi A, Khan I, Ngah Saaya N . Epidemiology and Clinical Features of Adult Patients with Psoriasis in Malaysia: 10-Year Review from the Malaysian Psoriasis Registry (2007-2016). Dermatol Res Pract. 2018; 2018:4371471. PMC: 5937568. DOI: 10.1155/2018/4371471. View

18.

Phan C, Sigal M, Esteve E, Reguiai Z, Barthelemy H, Beneton N . Psoriasis in the elderly: epidemiological and clinical aspects, and evaluation of patients with very late onset psoriasis. J Eur Acad Dermatol Venereol. 2014; 30(1):78-82. DOI: 10.1111/jdv.12850. View

19.

Fry L, Baker B . Triggering psoriasis: the role of infections and medications. Clin Dermatol. 2007; 25(6):606-15. DOI: 10.1016/j.clindermatol.2007.08.015. View

20.

Tsai T, Wang T, Hung S, Tsai P, Schenkel B, Zhang M . Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan. J Dermatol Sci. 2011; 63(1):40-6. DOI: 10.1016/j.jdermsci.2011.03.002. View