Effect of Human Chorionic Gonadotropin Injection Before Frozen Embryo Transfer on Pregnancy Outcomes in Endometriosis-Associated Infertility

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2020 Dec 31

PMID 33381512

Citations 5

Authors

Yanbo Du

Lei Yan

Mei Sun

Yan Sheng

Xiufang Li

Zhenhua Feng

Rong Tang

Affiliations

Soon will be listed here.

Abstract

The aim of this study was to investigate the effect of human chorionic gonadotropin (hCG) in hormone replacement (HT) regime for frozen thawed embryo transfer in women with endometriosis (EM). We performed a retrospective, database-search, cohort study and included data on EM patients who underwent frozen embryo transfer (FET) between January 1, 2009 and August 31, 2018. According to the protocols for FET cycle, the patients were divided into two groups: control group ( = 296) and hCG group ( = 355). Clinical pregnancy rate, live birth rate, early abortion rate, late abortion rate, and ectopic pregnancy rate were compared between the two groups. There was a significant increase in clinical pregnancy rate in the hCG group (57.7 vs. 49%, = 0.027) compared with the control group. The live birth rate in the hCG group (45.6 vs. 38.5%, = 0.080) was also elevated, but this difference was not statistically significant. hCG administration in HT regime for FET increases the pregnancy rate in women with EM.

Citing Articles

Effect of human chorionic gonadotropin injection before frozen-thawed embryo transfer: A retrospective cohort study.

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Effect of Human Chorionic Gonadotropin Injection Before Frozen Embryo Transfer on Pregnancy Outcomes in Endometriosis-Associated Infertility.

Du Y, Yan L, Sun M, Sheng Y, Li X, Feng Z Front Med (Lausanne). 2020; 7:592921.

PMID: 33381512 PMC: 7768008. DOI: 10.3389/fmed.2020.592921.

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