Metastatic Angiosarcoma of Unknown Primary Site Misdiagnosed As Tuberculosis

Overview

Journal Clin Case Rep

Date 2020 Dec 28

PMID 33363871

Citations 1

Authors

Mwakyula Issakwisa

Ngwilo Mwakyusa

Liset Torres

Cecilia Ngatunga

Baraka Chaula

Haika Maro

Lazaro Mboma

Irene Nguma

Lamla Nqwata

Leodegard Mujwahuzi

Affiliations

Soon will be listed here.

Abstract

Tuberculosis in endemic areas is likely to be overdiagnosed in patients with atypical clinical and imaging findings mimicking tuberculosis, as in our case of angiosarcoma. Detailed history, physical examination, imaging, and histopathology avert diagnosis of tumors as tuberculosis in resource-limited settings, where countless diseases have common clinical and imaging presentations.

Citing Articles

Metastatic angiosarcoma of unknown primary site misdiagnosed as tuberculosis.

Issakwisa M, Mwakyusa N, Torres L, Ngatunga C, Chaula B, Maro H Clin Case Rep. 2020; 8(12):3018-3023.

PMID: 33363871 PMC: 7752315. DOI: 10.1002/ccr3.3243.

References

Delacruz V, Jorda M, Gomez-Fernandez C, Benedetto P, Ganjei P . Fine-needle aspiration diagnosis of angiosarcoma of the spleen: a case report and review of the literature. Arch Pathol Lab Med. 2005; 129(8):1054-6. DOI: 10.5858/2005-129-1054-FADOAO. View

Huang J, Mackillop W . Increased risk of soft tissue sarcoma after radiotherapy in women with breast carcinoma. Cancer. 2001; 92(1):172-80. DOI: 10.1002/1097-0142(20010701)92:1<172::aid-cncr1306>3.0.co;2-k. View

Meis-Kindblom J, Kindblom L . Angiosarcoma of soft tissue: a study of 80 cases. Am J Surg Pathol. 1998; 22(6):683-97. DOI: 10.1097/00000478-199806000-00005. View

Oliviero U, Bonadies G, Bosso G, Foggia M, Apuzzi V, Cotugno M . Impaired diastolic function in naïve untreated human immunodeficiency virus infected patients. World J Cardiol. 2010; 2(4):98-103. PMC: 2999046. DOI: 10.4330/wjc.v2.i4.98. View

Shimabukuro I, Yatera K, Noguchi S, Kawanami Y, Iwanami T, Nishida C . Primary Pulmonary Angiosarcoma Presenting with Hemoptysis and Ground-Glass Opacity: A Case Report and Literature Review. Tohoku J Exp Med. 2015; 237(4):273-8. DOI: 10.1620/tjem.237.273. View

Wang Q, Zhao T, Mi B, Zhang Y, Wei R, Tong H . Primary Colonic Angiosarcoma Seen in a Patient on Calcium Channel Blocker: A Case Report with Summary Analysis of 32 Other Cases from the Literature. Am J Case Rep. 2018; 19:254-261. PMC: 5850845. DOI: 10.12659/ajcr.907287. View

Young R, Brown N, Reed M, Hughes D, Woll P . Angiosarcoma. Lancet Oncol. 2010; 11(10):983-91. DOI: 10.1016/S1470-2045(10)70023-1. View

Bocklage T, Leslie K, Yousem S, Colby T . Extracutaneous angiosarcomas metastatic to the lungs: clinical and pathologic features of twenty-one cases. Mod Pathol. 2001; 14(12):1216-25. DOI: 10.1038/modpathol.3880463. View

Bendel E, Maleszewski J, Araoz P . Imaging sarcomas of the great vessels and heart. Semin Ultrasound CT MR. 2011; 32(5):377-404. DOI: 10.1053/j.sult.2011.06.001. View

10.

Scott M, Portnow L, Morris C, Marcus Jr R, Mendenhall N, Mendenhall W . Radiation therapy for angiosarcoma: the 35-year University of Florida experience. Am J Clin Oncol. 2012; 36(2):174-80. DOI: 10.1097/COC.0b013e3182436ea3. View

11.

Sindhu S, Gimber L, Cranmer L, McBride A, Kraft A . Angiosarcoma treated successfully with anti-PD-1 therapy - a case report. J Immunother Cancer. 2017; 5(1):58. PMC: 5514460. DOI: 10.1186/s40425-017-0263-0. View

12.

Pervaiz N, Colterjohn N, Farrokhyar F, Tozer R, Figueredo A, Ghert M . A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma. Cancer. 2008; 113(3):573-81. DOI: 10.1002/cncr.23592. View

13.

Murinello A, Mendonca P, Abreu A, Santos A, Roquete J, Pinto E . Cardiac angiosarcoma--a review. Rev Port Cardiol. 2007; 26(5):577-84. View

14.

Gaballah A, Jensen C, Palmquist S, Pickhardt P, Duran A, Broering G . Angiosarcoma: clinical and imaging features from head to toe. Br J Radiol. 2017; 90(1075):20170039. PMC: 5594986. DOI: 10.1259/bjr.20170039. View

15.

Palmerini E, Maki R, Staals E, Alberghini M, Antonescu C, Ferrari C . Primary angiosarcoma of bone: a retrospective analysis of 60 patients from 2 institutions. Am J Clin Oncol. 2013; 37(6):528-34. PMC: 3681918. DOI: 10.1097/COC.0b013e31827defa1. View

16.

Peterson M, BARON R, Rankin S . Hepatic angiosarcoma: findings on multiphasic contrast-enhanced helical CT do not mimic hepatic hemangioma. AJR Am J Roentgenol. 2000; 175(1):165-70. DOI: 10.2214/ajr.175.1.1750165. View

17.

Issakwisa M, Mwakyusa N, Torres L, Ngatunga C, Chaula B, Maro H . Metastatic angiosarcoma of unknown primary site misdiagnosed as tuberculosis. Clin Case Rep. 2020; 8(12):3018-3023. PMC: 7752315. DOI: 10.1002/ccr3.3243. View

18.

STEWART F, TREVES N . Lymphangiosarcoma in postmastectomy lymphedema; a report of six cases in elephantiasis chirurgica. Cancer. 1948; 1(1):64-81. DOI: 10.1002/1097-0142(194805)1:1<64::aid-cncr2820010105>3.0.co;2-w. View

19.

Treglia G, Cardillo G, Graziano P . A rare case of primary pulmonary epithelioid angiosarcoma detected by (18)F-FDG PET/CT. Clin Nucl Med. 2013; 39(5):450-2. DOI: 10.1097/RLU.0b013e318292f3b3. View

20.

Brown B, Mason T, Ballard W, Wickliffe C, Bone D . Cardiac angiosarcoma: a case report. J Med Assoc Ga. 1991; 80(8):435-8. View