The Ubiquitylome of Developing Cortical Neurons

Overview

Journal MicroPubl Biol

Specialty Biology

Date 2020 Dec 4

PMID 33274322

Citations 3

Authors

Shalini Menon

Dennis Goldfarb

Emily M Cousins

M Ben Major

Stephanie L Gupton

Affiliations

Soon will be listed here.

Citing Articles

Proteome and ubiquitinome analyses of the brain cortex in K18- mice infected with SARS-CoV-2.

Wang Q, Peng W, Yang Y, Wu Y, Han R, Ding T iScience. 2024; 27(9):110602.

PMID: 39211577 PMC: 11357812. DOI: 10.1016/j.isci.2024.110602.

The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.

McCormick L, Evans E, Barker N, Herring L, Diering G, Gupton S Mol Biol Cell. 2024; 35(5):ar67.

PMID: 38507236 PMC: 11151106. DOI: 10.1091/mbc.E23-12-0476.

The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.

McCormick L, Evans E, Barker N, Herring L, Diering G, Gupton S bioRxiv. 2024; .

PMID: 38260647 PMC: 10802335. DOI: 10.1101/2023.12.31.573790.

References

Menon S, Goldfarb D, Ho C, Cloer E, Boyer N, Hardie C . The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis. Mol Biol Cell. 2020; 32(4):314-330. PMC: 8098814. DOI: 10.1091/mbc.E20-10-0622. View

Xu G, Paige J, Jaffrey S . Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol. 2010; 28(8):868-73. PMC: 2946519. DOI: 10.1038/nbt.1654. View

Berti C, Messali S, Ballabio A, Reymond A, Meroni G . TRIM9 is specifically expressed in the embryonic and adult nervous system. Mech Dev. 2002; 113(2):159-62. DOI: 10.1016/s0925-4773(02)00013-8. View

Menon S, Boyer N, Winkle C, McClain L, Hanlin C, Pandey D . The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance. Dev Cell. 2015; 35(6):698-712. PMC: 4707677. DOI: 10.1016/j.devcel.2015.11.022. View

Winkle C, McClain L, Valtschanoff J, Park C, Maglione C, Gupton S . A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching. J Cell Biol. 2014; 205(2):217-32. PMC: 4003241. DOI: 10.1083/jcb.201311003. View

Boyer N, McCormick L, Menon S, Urbina F, Gupton S . A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance. J Cell Biol. 2019; 219(1). PMC: 7039193. DOI: 10.1083/jcb.201902088. View

Plooster M, Menon S, Winkle C, Urbina F, Monkiewicz C, Phend K . TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching. Mol Biol Cell. 2017; 28(18):2374-2385. PMC: 5576901. DOI: 10.1091/mbc.E16-08-0594. View

Tyanova S, Temu T, Sinitcyn P, Carlson A, Hein M, Geiger T . The Perseus computational platform for comprehensive analysis of (prote)omics data. Nat Methods. 2016; 13(9):731-40. DOI: 10.1038/nmeth.3901. View

Winkle C, Olsen R, Kim H, Moy S, Song J, Gupton S . Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory. J Neurosci. 2016; 36(18):4940-58. PMC: 4854964. DOI: 10.1523/JNEUROSCI.3876-15.2016. View

10.

Fischer D, van Dijk R, van Tijn P, Hobo B, Verhage M, van der Schors R . Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin. Neurobiol Aging. 2008; 30(6):847-63. DOI: 10.1016/j.neurobiolaging.2008.06.009. View

11.

Kwiatkowski A, Rubinson D, Dent E, van Veen J, Leslie J, Zhang J . Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007; 56(3):441-55. DOI: 10.1016/j.neuron.2007.09.008. View

12.

Ritchie M, Phipson B, Wu D, Hu Y, Law C, Shi W . limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015; 43(7):e47. PMC: 4402510. DOI: 10.1093/nar/gkv007. View

13.

Boyer N, Monkiewicz C, Menon S, Moy S, Gupton S . Mammalian TRIM67 Functions in Brain Development and Behavior. eNeuro. 2018; 5(3). PMC: 6002264. DOI: 10.1523/ENEURO.0186-18.2018. View

14.

Perez-Riverol Y, Csordas A, Bai J, Bernal-Llinares M, Hewapathirana S, Kundu D . The PRIDE database and related tools and resources in 2019: improving support for quantification data. Nucleic Acids Res. 2018; 47(D1):D442-D450. PMC: 6323896. DOI: 10.1093/nar/gky1106. View

15.

Urbina F, Gomez S, Gupton S . Spatiotemporal organization of exocytosis emerges during neuronal shape change. J Cell Biol. 2018; 217(3):1113-1128. PMC: 5839795. DOI: 10.1083/jcb.201709064. View

16.

Nielsen M, Vermeulen M, Bonaldi T, Cox J, Moroder L, Mann M . Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry. Nat Methods. 2008; 5(6):459-60. DOI: 10.1038/nmeth0608-459. View