Secondary Epiretinal Membrane After Ex-Press Glaucoma Filtration Device Implant

Overview

Journal Graefes Arch Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2020 Dec 1

PMID 33259000

Citations 3

Authors

Pasquale Loiudice

Francesco Sartini

Michele Figus

Marco Nardi

Chiara Posarelli

Giamberto Casini

Affiliations

Soon will be listed here.

Abstract

Purpose: To estimate the frequency of epiretinal membrane (ERM) in eyes with primary open-angle glaucoma (POAG) treated with Ex-Press shunt implant. Secondarily, we aimed to assess the role of concomitant cataract surgery and the impact of the ERM on central foveal thickness and macular volume.

Methods: In this prospective, consecutive, case-control study, we enrolled 54 patients affected by PAOG and scheduled for Ex-Press device implant with or without contemporary phacoemulsification. Contralateral eyes affected by POAG and receiving anti-glaucomatous eyedrops constituted the control group. Complete ophthalmologic evaluation and spectral-domain optical coherence tomography (OCT) were performed before and 1, 3 and 6 months after surgery.

Results: Twenty-six eyes received the Ex-Press implant alone, and 28 eyes underwent the combined procedure. Six months postoperatively, we observed 18 (33%) cases of ERM: 15 (28%) of cellophane macular reflex (CMR) and 3 (6%) of pre-macular fibrosis (PMF). In the control group, 9 (17%) eyes developed an ERM: 8 (15%) were CMR, and 1 (2%) was PMF. The frequency of ERM statistically differs between treated and contralateral eyes (P = 0.032, χ test). The ERM frequency did not statically differ between eyes subjected to simple or combined surgery (P = 0.846, χ test). Mean central foveal thickness and mean macular volume did not significantly differ between groups.

Conclusion: The Ex-Press glaucoma shunt may increase the risk of ERM onset regardless of the concomitant cataract surgery; however, most cases were cellophane macular reflex with limited functional and anatomical impact.

Citing Articles

Does Laser Iridotomy Cause Secondary Epiretinal Membrane?.

Akmaz O, Talay N Turk J Ophthalmol. 2024; 54(5):263-267.

PMID: 39463150 PMC: 11589235. DOI: 10.4274/tjo.galenos.2024.61094.

Epiretinal membrane development after Ex-Press glaucoma filtration device implant: 2-year results of a case control study.

Sartini F, Menchini M, Palma A, Casini G, Figus M Int Ophthalmol. 2024; 44(1):93.

PMID: 38367121 PMC: 10874323. DOI: 10.1007/s10792-024-02958-5.

Evaluation of New and Preexisting Epiretinal Membranes Following Glaucoma Filtration Surgery.

Aoki R, Dote S, Oogi S, Nagata Y, Ueda K, Terao E Cureus. 2023; 15(10):e46441.

PMID: 37927709 PMC: 10622603. DOI: 10.7759/cureus.46441.

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