Update on Latest Advances in Time-of-flight PET

Overview

Journal Phys Med

Specialties Biophysics
General Medicine

Date 2020 Nov 19

PMID 33212421

Citations 24

Authors

Suleman Surti

Joel S Karp

Affiliations

Soon will be listed here.

Abstract

This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.

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