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Analytical Ultracentrifugation: Still the Gold Standard That Offers Multiple Solutions

Overview
Journal Eur Biophys J
Specialty Biophysics
Date 2020 Nov 19
PMID 33211149
Citations 1
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Abstract

Understanding the nature of macromolecules and their interactions in solution underpins many fields, including biology, chemistry and materials science. The 24th International Analytical Ultracentrifugation Workshop and Symposium (AUC2019, held in Christchurch, New Zealand, August 2019), brought together 77 international delegates to highlight recent developments in the field. There was a focus on analytical ultracentrifugation, although we recognise that this is but one of the key methods in the biophysicist's toolkit. Many of the presentations showcased the versatility of analytical ultracentrifugation and how such experiments are integrated with other solution techniques, such as small-angle X-ray scattering, cryo-electron microscopy, isothermal titration calorimetry and more. This special issue emphasises a wide range of themes covered in the meeting, including carbohydrate chemistry, protein chemistry, polymer science, and macromolecular interactions.

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PMID: 33434434 PMC: 7941215. DOI: 10.1021/acs.analchem.0c05208.

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