Electrochemistry of Graphene Nanoplatelets Printed Electrodes for Cortical Direct Current Stimulation

Overview

Journal Front Neurosci

Date 2020 Nov 16

PMID 33192280

Citations 4

Authors

Andrzej Peplowski

Sanchit Rathi

Bartosz Piotrkowski

Robert Ziolkowski

Daniel Janczak

Jakub Krzeminski

Michael Brosch

Malgorzata Jakubowska

Affiliations

Soon will be listed here.

Abstract

Possible risks stemming from the employment of novel, micrometer-thin printed electrodes for direct current neural stimulation are discussed. To assess those risks, electrochemical methods are used, including cyclic voltammetry, square-wave voltammetry, and electrochemical impedance spectroscopy. Experiments were conducted in non-deoxidized phosphate-buffered saline to better emulate living organism conditions. Since preliminary results obtained have shown unexpected oxidation peaks in 0-0.4 V potential range, the source of those was further investigated. Hypothesized redox activity of printing paste components was disproven, supporting further development of proposed fabrication technology of stimulating electrodes. Finally, partial permeability and resulting electrochemical activity of underlying silver-based printed layers of the device were pointed as the source of potential tissue irritation or damage. Employing this information, electrodes with corrected design were investigated, yielding no undesired redox processes.

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