Detection of Sars-Cov-2 in the Air of Two Hospitals in Hermosillo, Sonora, México, Utilizing a Low-cost Environmental Monitoring System

Overview

Journal Int J Infect Dis

Publisher Elsevier

Specialty Infectious Diseases

Date 2020 Nov 6

PMID 33157295

Citations 10

Authors

Jorge Hernandez Lopez

Alvaro Santos Romo

Daniel Coronado Molina

Gerardo Alvarez Hernandez

Angel Benjamin Gutierrez Cureno

Magali Aviles Acosta

Carlos Andres Aviles Gaxiola

Marcos Jose Serrato Felix

Teresa Gollas Galvan

Affiliations

Soon will be listed here.

Abstract

Objective: The best way of preventing the dispersion of an infectious disease is decreasing the transmissibility of the pathogen. To achieve such a goal, it is important to have epidemiological surveillance to retrieve data about its routes of transmission and dispersion. This study investigated the possibility of SARS-CoV-2 detection using filtration through 0.22 μm pores.

Methods: A filtration system with vacuum pump was used for sampling, and molecular analysis was performed by RT-PCR for detecting the COVID-19 virus.

Results: It was found that SARS-CoV-2 could be detected in particulate matter trapped on 0.22 μm filters 3 h after air sampling, and the only contaminated areas were those near patient zones.

Conclusions: The results confirm the possibility of finding this virus in floating particulate matter in contaminated zones, with a simple and economic sampling method based on filtration technology through 0.22 μm pores and detection with molecular techniques (RT-PCR). The higher risk zones were those near patients with COVID-19.

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References

Guo Z, Wang Z, Zhang S, Li X, Li L, Li C . Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards, Wuhan, China, 2020. Emerg Infect Dis. 2020; 26(7):1583-1591. PMC: 7323510. DOI: 10.3201/eid2607.200885. View

Corman V, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu D . Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020; 25(3). PMC: 6988269. DOI: 10.2807/1560-7917.ES.2020.25.3.2000045. View

Zhang J, Wang S, Xue Y . Fecal specimen diagnosis 2019 novel coronavirus-infected pneumonia. J Med Virol. 2020; 92(6):680-682. PMC: 7228355. DOI: 10.1002/jmv.25742. View

Wu S, Wang Y, Jin X, Tian J, Liu J, Mao Y . Environmental contamination by SARS-CoV-2 in a designated hospital for coronavirus disease 2019. Am J Infect Control. 2020; 48(8):910-914. PMC: 7214329. DOI: 10.1016/j.ajic.2020.05.003. View

Zhang R, Li Y, Zhang A, Wang Y, Molina M . Identifying airborne transmission as the dominant route for the spread of COVID-19. Proc Natl Acad Sci U S A. 2020; 117(26):14857-14863. PMC: 7334447. DOI: 10.1073/pnas.2009637117. View

Holshue M, DeBolt C, Lindquist S, Lofy K, Wiesman J, Bruce H . First Case of 2019 Novel Coronavirus in the United States. N Engl J Med. 2020; 382(10):929-936. PMC: 7092802. DOI: 10.1056/NEJMoa2001191. View

Amirian E . Potential fecal transmission of SARS-CoV-2: Current evidence and implications for public health. Int J Infect Dis. 2020; 95:363-370. PMC: 7195510. DOI: 10.1016/j.ijid.2020.04.057. View

Ghinai I, McPherson T, Hunter J, Kirking H, Christiansen D, Joshi K . First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. Lancet. 2020; 395(10230):1137-1144. PMC: 7158585. DOI: 10.1016/S0140-6736(20)30607-3. View

Li D, Wang D, Dong J, Wang N, Huang H, Xu H . False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases. Korean J Radiol. 2020; 21(4):505-508. PMC: 7082661. DOI: 10.3348/kjr.2020.0146. View

10.

Ong S, Tan Y, Chia P, Lee T, Ng O, Wong M . Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient. JAMA. 2020; 323(16):1610-1612. PMC: 7057172. DOI: 10.1001/jama.2020.3227. View

11.

Wang W, Xu Y, Gao R, Lu R, Han K, Wu G . Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020; 323(18):1843-1844. PMC: 7066521. DOI: 10.1001/jama.2020.3786. View

12.

Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H . Evidence for Gastrointestinal Infection of SARS-CoV-2. Gastroenterology. 2020; 158(6):1831-1833.e3. PMC: 7130181. DOI: 10.1053/j.gastro.2020.02.055. View

13.

Caorsi P B, Sakurada Z A, Ulloa F M, Pezzani V M, Latorre O P . [Bacteriological quality of air in a ward for sterile pharmaceutical preparations]. Rev Chilena Infectol. 2011; 28(1):14-8. DOI: /S0716-10182011000100003. View

14.

Fathizadeh H, Maroufi P, Momen-Heravi M, Dao S, Kose S, Ganbarov K . Protection and disinfection policies against SARS-CoV-2 (COVID-19). Infez Med. 2020; 28(2):185-191. View

15.

Chen K, Wang M, Huang C, Kinney P, Anastas P . Air pollution reduction and mortality benefit during the COVID-19 outbreak in China. Lancet Planet Health. 2020; 4(6):e210-e212. PMC: 7220178. DOI: 10.1016/S2542-5196(20)30107-8. View

16.

Faridi S, Niazi S, Sadeghi K, Naddafi K, Yavarian J, Shamsipour M . A field indoor air measurement of SARS-CoV-2 in the patient rooms of the largest hospital in Iran. Sci Total Environ. 2020; 725:138401. PMC: 7194859. DOI: 10.1016/j.scitotenv.2020.138401. View

17.

Kampf G, Todt D, Pfaender S, Steinmann E . Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hosp Infect. 2020; 104(3):246-251. PMC: 7132493. DOI: 10.1016/j.jhin.2020.01.022. View

18.

Wang J, Feng H, Zhang S, Ni Z, Ni L, Chen Y . SARS-CoV-2 RNA detection of hospital isolation wards hygiene monitoring during the Coronavirus Disease 2019 outbreak in a Chinese hospital. Int J Infect Dis. 2020; 94:103-106. PMC: 7165090. DOI: 10.1016/j.ijid.2020.04.024. View

19.

Wu D, Wu T, Liu Q, Yang Z . The SARS-CoV-2 outbreak: What we know. Int J Infect Dis. 2020; 94:44-48. PMC: 7102543. DOI: 10.1016/j.ijid.2020.03.004. View

20.

van Doremalen N, Bushmaker T, Morris D, Holbrook M, Gamble A, Williamson B . Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med. 2020; 382(16):1564-1567. PMC: 7121658. DOI: 10.1056/NEJMc2004973. View