Effect of Biologic Materials on the Outcomes of Horizontal Alveolar Ridge Augmentation: A Retrospective Study

Overview

Journal Clin Exp Dent Res

Publisher Wiley

Specialty Dentistry

Date 2020 Nov 5

PMID 33150685

Citations 3

Authors

Janina Golob Deeb

Amy Reichert

Caroline K Carrico

Daniel M Laskin

George R Deeb

Affiliations

Soon will be listed here.

Abstract

Purpose: The purpose of this study was to investigate if the addition of biologic agents to a particulate bone graft enhances horizontal ridge augmentation outcomes in terms of bone dimensions, bone density, and successful implant placement.

Materials And Methods: A retrospective chart review was done to assess the clinical and radiographic outcomes in 52 horizontal ridge augmentation sites in 43 patients. Information was gathered regarding surgical technique, type of graft material, biologic agents used (PRP or rhPDGF-BB), method of space maintenance, and achieved alveolar ridge width and bone density changes as quantified on CBCT scans.

Results: The use of tenting screws, a resorbable membrane, and a combination of particulate allogenic and xenogenic bone graft material provided an average horizontal bone gain of 3.6 mm in the 52 augmented sites. There was no statistically significant difference observed in the amount of horizontal bone gain between sites treated with the addition of biologic agents (n = 21), or with a particulate bone graft alone (n = 31). A marginally statistically significant difference was found in the density of the grafted bone with the addition of biologics (p value = .0653).

Conclusion: The addition of biologic agents to the graft materials did not have a significant effect on the amount of horizontal bone gain or successful implant placement; however, it marginally enhanced the bone density of the grafted area.

Citing Articles

Guided Bone Regeneration: CGF and PRF Combined With Various Types of Scaffolds-A Systematic Review.

Inchingolo F, Inchingolo A, Latini G, de Ruvo E, Campanelli M, Palermo A Int J Dent. 2024; 2024:4990295.

PMID: 39669891 PMC: 11637628. DOI: 10.1155/ijod/4990295.

Tooth as graft material: Histologic study.

Minetti E, Corbella S, Taschieri S, Canullo L Clin Implant Dent Relat Res. 2022; 24(4):488-496.

PMID: 35507503 PMC: 9544007. DOI: 10.1111/cid.13097.

Effect of biologic materials on the outcomes of horizontal alveolar ridge augmentation: A retrospective study.

Deeb J, Reichert A, Carrico C, Laskin D, Deeb G Clin Exp Dent Res. 2020; 7(2):147-155.

PMID: 33150685 PMC: 8019766. DOI: 10.1002/cre2.343.

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