Dendritic Cells in the Pathogenesis of Rheumatoid Arthritis

Overview

Journal Rheumatol Int

Specialty Rheumatology

Date 1987 Jan 1

PMID 3313661

Authors

L M March

Affiliations

Soon will be listed here.

Abstract

The cause of rheumatoid arthritis is unknown. It appears that abnormal or overstimulated cell-mediated immune mechanisms are operating. Dendritic cells, with their potent antigen presenting and immunostimulatory properties, have been found in increased numbers of rheumatoid synovial fluids and membranes. It is postulated that these cells play a key role in inducing and perpetuating the immune response with subsequent synovial proliferation and joint destruction.

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