Isolation and Complete Genome Sequencing of the Virulent Phage VB_EcoS_XY3 Infecting Multidrug-resistant Escherichia Coli

Overview

Journal Arch Virol

Specialty Microbiology

Date 2020 Oct 25

PMID 33099693

Citations 1

Authors

Pan Fu

Qiang Zhao

Li Shi

Qin Xiong

Hongxia Xu

Senmao Cai

Qianqian Xu

Xiaodong Sun

Ming Sang

Affiliations

Soon will be listed here.

Abstract

A virulent phage, named vB_EcoS_XY3, was isolated from hospital wastewater in Xiangyang, China. Its morphological characteristics, growth parameters, adsorption rate, and pH and temperature stability were determined. Phage vB_EcoS_XY3 was found to be able to infect Escherichia coli laboratory strains and also some multidrug-resistant E. coli strains. Its complete genome consists of 51,345 base pairs of double-stranded DNA with an average GC content of 55.24% and 85 putative protein-coding genes. Forty-four genes were annotated with known functions. These results will not only provide further insights into E. coli phages but also have implications for the development of potential biocontrol agents.

Citing Articles

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Ye Y, Tong G, Chen G, Huang L, Huang L, Jiang X Virus Res. 2023; 336:199193.

PMID: 37579848 PMC: 10480305. DOI: 10.1016/j.virusres.2023.199193.

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