Prevalence of Infection Among Type 2 Diabetes Mellitus

Overview

Journal Adv Biomed Res

Specialty Biomedical Engineering

Date 2020 Oct 19

PMID 33072639

Citations 10

Authors

Abdulbari Bener

Ahmet Faruk Agan

Abdulla O A A Al-Hamaq

Cem Cahit Barisik

Mustafa Ozturk

Abdulkadir Omer

Affiliations

Soon will be listed here.

Abstract

Background: Several conducted studies have reported a higher and more frequent infection rate in type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the prevalence and its association between infection and T2DM.

Materials And Methods: A case and control study was conducted based on 529 T2DM patients and 529 control. was assessed by Serum anti- immunoglobulin G (IgG) and IgA. Furthermore, patients were investigated for fasting blood glucose (FBG) levels, glycosylated hemoglobin (HbA1c), serum cholesterol, and other biochemistry parameters.

Results: The findings showed a positive significantly higher antibody titer for infection (IgA > 250) in diabetic patients (50.7%) compared to controls (38.2%) ( < 0.001). Similarly, infection for IgG > 300 titer was higher in T2DM patients (73.5%) compared to controls 61.8%) ( < 0.001). Further, the mean values were statistically significant diabetes with infection for IgG > 300 titer and IgA > 250 titer, regarding Vitamin D, HbA1C ( < 0.001), FBG, calcium, creatinine, total cholesterol, LHDL, triglyceride levels, uric acid, bilirubin, thyroid-stimulating hormone (TSH), and systolic and diastolic blood pressure. The diabetic patients showed higher prevalence rate of symptoms than controls included: hypertension (14.3%), vomiting (15.5%), muscular symptoms (35.2%), bloating/distension (13.2%), abdominal pain (17%), nausea (9.6%), anemia (17%), kidneys (20.8%), chronic bronchitis (14.7%), gastrointestinal (23.8%), and diarrhea (20.4%).

Conclusions: The current study revealed that infections were significantly higher in diabetic patients compared to controls. Furthermore, T2DM patients infected with reported a higher prevalence rate of symptoms than .

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