Rapid Emergence of Multidrug-Resistance Among Gram Negative Isolates at a Tertiary Pediatric and Maternity Hospital in Ulaanbaatar, Mongolia

Overview

Journal Cent Asian J Glob Health

Date 2020 Oct 16

PMID 33062401

Citations 1

Authors

Susanna Felsenstein

Sarantsetseg Bira

Narangerel Altanmircheg

Enkhtur Shonkhuuz

Ariuntuya Ochirpurev

David Warburton

Affiliations

Soon will be listed here.

Abstract

Introduction: Information on microbiological and susceptibility profiles of clinical isolates in Mongolia is scarce, hampering infection control and clinical care.

Methods: Species and resistance profiles of 6334 clinical gram negative isolates, collected at Mongolia's National Center for Maternal and Child Health between 2014 and 2017 were analyzed.

Results: Annual proportion of multidrug-resistance among and isolates increased from 2.8% to 16.6% and 3.5% to 22.6% respectively; isolates exhibiting susceptibilities suggestive of extended spectrum beta-lactamase (ESBL) production from 73% to 94%. By 2017, 60.6% of isolates were multidrug-resistant, most originated from intensive care wards. Enterobacteriaceae exhibiting susceptibility patterns suggestive of ESBL production and multidrug-resistant organisms were common and their incidence increased rapidly.

Conclusion: These findings will serve to build strategies to strengthen microbiological surveillance, diagnostics and infection control; and to develop empiric therapy and stewardship recommendations for Mongolia's largest Children's and Maternity hospital.

Citing Articles

Microbiological Spectrum of Osteoarticular Infections and Their Management in Mongolian Children.

Ulziibat M, Buettcher M, Altankhuyag U, Chuluunbaatar B, Mikhlay Z, Sharav C Glob Pediatr Health. 2024; 11:2333794X241298801.

PMID: 39564466 PMC: 11574899. DOI: 10.1177/2333794X241298801.

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